Corydalis Extract Tetrahydropalmatine (dl-THP)
Tetrahydropalmatine (THP), tseem hu ua dl-THP, Corydalin hydrochloride, los yog Corydalin Tube Extract, yog ib qho sib xyaw ua ke raws li isoquinoline alkaloid. Nws yog muab rho tawm los ntawm tuber ntawm Suav tshuaj ntsuab Corydalis yanhusuo. THP yog cov xim tsis muaj xim lossis daj daj daj crystalline nrog ib qho iab saj thiab melting point ntawm 147-149 ° C. Nws yog xyaum insoluble nyob rau hauv dej tab sis heev soluble nyob rau hauv ether, chloroform, thiab ethanol. Nws cov hydrochloride thiab sulfate ntsev yog soluble hauv dej.
THP tau kawm txog ntau yam teebmeem tshuaj, suav nrog nws cov tshuaj tua kab mob, tshuaj loog, neuroprotective, antiplatelet aggregation, antiulcer, antitumor, thiab tiv thaiv kev quav tshuaj. Nws ntseeg tau tias nws yuav siv nws cov teebmeem analgesic los ntawm kev hloov pauv hauv nruab nrab dopamine receptor kev ua haujlwm thiab tau pom muaj peev xwm tiv thaiv cov neurons los ntawm kev raug mob ischemic. Tsis tas li ntawd, THP tau pom tias muaj cov nyhuv antiplatelet sib sau ua ke thiab tau tshawb xyuas txog nws lub peev xwm hauv kev kho mob rwj, inhibiting qog cell loj hlob, thiab pab tiv thaiv kab mob.
Zuag qhia tag nrho, Tetrahydropalmatine (dl-THP) yog ib qho chaw sib xyaw nrog ntau yam tshuaj siv tshuaj thiab tau ua raws li kev tshawb fawb dav dav rau nws cov kev siv tshuaj kho mob. Yog xav paub ntxiv hu raugrace@biowaycn.com.
Nov yog cov khoom nta ntawm Tetrahydropalmatine (THP) nrog rau lawv cov txiaj ntsig kev noj qab haus huv:
1. Cov yam ntxwv ntawm cov tshuaj loog:THP nthuav tawm cov teebmeem analgesic los ntawm kev hloov pauv hauv nruab nrab dopamine receptor kev ua haujlwm, muab qhov mob nyem yam tsis muaj qhov tseem ceeb ntxiv.
2. Cov teebmeem Neuroprotective:THP tau pom tias muaj peev xwm tiv thaiv cov neurons los ntawm kev raug mob ischemic, txo cov neuronal apoptosis, thiab txo qis glutamate hauv lub hlwb, uas tuaj yeem ua rau nws cov khoom tiv thaiv neuroprotective.
3. Antiplatelet Aggregation:THP tau pom tias inhibit platelet aggregation, uas tuaj yeem txo qhov kev pheej hmoo ntawm cov ntshav txhaws thiab cov xwm txheej hauv plawv.
4. Kev them nyiaj yug plab plab:THP tau pom tias muaj kev tiv thaiv kab mob rwj thiab tuaj yeem pab txo qis cov kua qaub hauv plab, muab kev kho mob ntawm plab hnyuv thiab lwm yam mob.
5. Muaj peev xwm Antitumor Activity:THP tau qhia txog cov teebmeem cytotoxic ntawm cov qog hlwb, qhia txog lub luag haujlwm tseem ceeb hauv inhibiting qog kev loj hlob.
6. Anti-Addictive Properties:THP tau kawm txog nws lub peev xwm los txo cov tsos mob uas cuam tshuam nrog opioid thiab stimulant kev quav yeeb quav tshuaj, muab cov lus cog tseg hauv kev kho mob thiab kev tiv thaiv rov qab.
Cov yam ntxwv no qhia txog ntau yam txiaj ntsig kev noj qab haus huv thiab muaj peev xwm siv tshuaj kho mob ntawm Tetrahydropalmatine (THP).
Tetrahydropydalin (dl-THP) belongs rau isoquinoline alkaloids thiab yog ib qho alkaloid, feem ntau nyob rau hauv genus Corydalis lucidum (Yan Hu Suo), tab sis kuj nyob rau hauv lwm yam nroj tsuag xws li Stephania rotunda. Cov nroj tsuag no muaj kev siv tshuaj ntsuab hauv Suav tshuaj ntsuab.Corydalis yog ib tsob nroj uas muaj hnub nyoog ntev, 10 mus rau 20 cm siab, nrog cov tubers spherical. Nws cov stems saum toj no-hauv av yog luv thiab luv, nrog rau qhov ntsuas saum lub hauv paus. Basal nplooj thiab cauline nplooj zoo ib yam, nrog stalks; cauline nplooj yog hloov, nrog 2 thiab 3 compound nplooj. Cov nplooj thib ob feem ntau tawg tsis tiav thiab yog lobed tob. Cov nplooj me yog oblong, oval, lossis oval. Linear, txog 2 cm ntev, nrog blunt los yog ntse apex thiab zoo npoo. Nws inflorescence yog raceme-puab, nrog lub davhlau ya nyob twg los yog ntxeev nplooj; lub bracts yog dav lanceolate; paj yog reddish-ntsuab thiab loj hlob kab rov tav ntawm slender pedicels, uas yog hais txog 6 hli ntev; lub calyx ntog thaum ntxov; cov nplaim paj yog 4 thiab sab nrauv whorls yog 2 Cov ntu yog me ntsis loj dua, nrog cov npoo liab dawb thiab xiav-ntsuab liab. Nws muaj ib ntu sab saud, thiab tus Tsov tus tw txuas mus rau hauv ib lub spur ntev. Qhov ntev spur suav txog ib nrab ntawm tag nrho qhov ntev. Sab hauv 2 ntu yog nqaim dua li sab nraud 2 ntu. Sab saum toj kawg nkaus yog xiav-ntsuab thiab kho, thiab sab qis yog liab dawb; Lub stamens yog 6, thiab cov filaments txuas rau hauv ob pawg, txhua tus muaj 3 anthers; lub zes qe menyuam yog tiaj-cylindrical, style yog luv thiab nyias, thiab stigma yog 2, zoo li tus npauj npaim me me. Nws cov txiv hmab txiv ntoo yog capsule. Corydalis feem ntau yog tsim nyob rau hauv roob los yog nyom. Cov chaw tsim khoom tseem ceeb suav nrog Zhejiang, Hebei, Shandong, Jiangsu, thiab lwm qhov chaw.
Kev tsom xam | Specification |
Assay | Tetrahydropalmatine ≥98% |
Qhov tshwm sim | Lub teeb daj hmoov rau dawb hmoov |
Tshauv | ≤ 0.5% |
Moisture | ≤ 5.0% |
Tshuaj tua kab | Tsis zoo |
Cov hlau hnyav | ≤10ppm |
Pb | ≤ 2.0ppm |
As | ≤ 2.0ppm |
tsw | Yam ntxwv |
Particle loj | 100% txog 80 mesh |
Microbiological: | |
Tag nrho cov kab mob | ≤1000cfu / g |
Fungi | ≤100cfu / g |
Salmgosella | Tsis zoo |
Coli | Tsis zoo |
Ntawm no yog cov khoom thov kev lag luam ntawm Tetrahydropalmatine (THP):
1. Pharmaceuticals:THP yog siv nyob rau hauv kev lag luam kws tshuaj los tsim tshuaj kho mob thiab tshuaj tiv thaiv neuroprotective.
2. Nutraceuticals:THP yog siv rau hauv kev lag luam nutraceutical rau kev tsim cov tshuaj pab txhawm rau txo qhov mob thiab txhawb kev noj qab haus huv hauv plab.
3. Biotechnology:THP pom cov ntawv thov hauv biotechnology rau kev tshawb fawb txog kev kho mob antiplatelet thiab muaj peev xwm kho mob qog noj ntshav.
4. Kev Kho Mob:THP tau muab tso rau hauv cov khoom kho mob rau kev tswj kev quav tshuaj thiab tshem tawm cov tsos mob cuam tshuam nrog kev siv tshuaj opioid thiab stimulant siv.
5. Cosmeceuticals:THP tau tshawb fawb hauv cosmeceuticals rau cov tawv nqaij noj qab haus huv thiab kev siv tshuaj tiv thaiv.
Cov kev lag luam no qhia txog ntau yam kev siv peev txheej ntawm Tetrahydropalmatine (THP) hauv ntau yam khoom tsim thiab kev tshawb fawb.
Peb cov khoom raug tsim los siv cov kev tswj xyuas nruj nruj thiab ua raws li cov txheej txheem ntau lawm. Peb ua qhov tseem ceeb ntawm kev nyab xeeb thiab zoo ntawm peb cov khoom, xyuas kom meej tias nws ua tau raws li cov kev cai thiab cov ntawv pov thawj kev lag luam. Qhov kev cog lus rau kev ua tau zoo yog txhawm rau tsim kev ntseeg siab thiab kev ntseeg siab hauv kev ntseeg ntawm peb cov khoom. Cov txheej txheem ntau lawm yog raws li nram no:
Qhia
Hauv 100kg, 3-5 Hnub
Qhov rooj rau qhov rooj kev pabcuam yooj yim tuaj tos cov khoom
Los ntawm Hiav Txwv
Tshaj 300kg, Nyob ib ncig ntawm 30 Hnub
Chaw nres nkoj rau chaw nres nkoj kev pab cuam clearance broker xav tau
Los ntawm Cua
100kg-1000kg, 5-7days
Tshav dav hlau mus rau tshav dav hlau kev pab cuam clearance broker xav tau
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