Xov Xwm - Cov Menyuam Mos Noj Tau Nervonic Acid?

I. Kev Taw Qhia

Cov txiaj ntsig ntawm Nervonic Acid Hmoov1

Ntau tus niam txiv xav paub seb cov menyuam mos puas tuaj yeem noj cov kua qaub nervonic. Ua ntej teb cov lus nug no, nws yog ib qho tseem ceeb kom nkag siab txog cov peev txheej ntawm cov kua qaub nervonic. Vim tias cov mis niam muaj cov kua qaub nervonic, ib tug neeg yuav nug seb cov mis niam puas tsis haum rau kev noj. Tab sis dhau ntawm cov mis niam, cov menyuam mos hnub nyoog qis dua 3 xyoos puas tuaj yeem noj cov kua qaub nervonic los ntawm lwm qhov chaw?

II. Nervonic Acid yog dab tsi?

Nervonic acid, tseem hu ua selacholeic acid, yog lub npe scientific hu ua cis-15-tetracosenoic acid. Nws yog ib hom omega-9 monounsaturated fatty acid. Vim nws thawj zaug pom hauv cov hlab ntsha ntawm cov tsiaj txhu, nws feem ntau hu ua nervonic acid.

Nervonic acid yog ib feem ntawm cov biological membranes, feem ntau pom muaj nyob rau hauv daim ntawv ntawm glycolipids thiab sphingomyelins hauv cov khoom dawb ntawm lub hlwb tib neeg, retina, phev, thiab cov ntaub so ntswg ntawm lub paj hlwb.

III. Cov txiaj ntsig ntawm Nervonic Acid

Lub npe "nervonic acid" qhia txog nws lub luag haujlwm tseem ceeb: pab txhawb lub paj hlwb. Tsis tas li ntawd, vim nws tsis muaj roj ntau, nws kuj muaj txiaj ntsig zoo rau lub plawv thiab cov hlab ntsha. Cia peb kawm ntxiv:

Txhawb Kev Loj Hlob ntawm Lub Hlwb

Kev sib piv ntawm cov menyuam mos uas yug tsis tau lub sijhawm thiab cov menyuam mos uas yug puv sijhawm tau qhia tias muaj cov kua qaub nervonic ntau dua hauv lub hlwb ntawm cov menyuam mos uas yug puv sijhawm. Cov kev tshawb fawb qhia tias cov kua qaub nervonic yuav cuam tshuam rau kev loj hlob ntawm lub taub hau ntawm cov menyuam mos.
Cov kua qaub nervonic tswj kev ua haujlwm ntawm lub hlwb cell membrane, txhim kho kev sib kis cov ntaub ntawv ntawm cov hlwb cell thiab txhawb kev ua haujlwm ntawm calcium ion. Kev tshawb fawb txog tsiaj txhu txhawb qhov no, qhia tias kev noj cov tshuaj nervonic acid tuaj yeem txhim kho kev kawm thiab kev nco qab hauv cov nas ib txwm thiab cov nas uas tsis nco qab zoo. Yog li, nws tau xav tias cov kua qaub nervonic tuaj yeem txhim kho kev nco qab thiab kev paub ntawm tib neeg.

Txhim kho kev tsom mus rau qhov tseem ceeb

Kev Mob Siab Tsis Txaus (ADHD) yog tus yam ntxwv los ntawm kev tsis mloog zoo, kev xav ua ntej, thiab kev ua haujlwm ntau dhau. ADHD tuaj yeem ua rau kev kawm tsis tau zoo, kev sib raug zoo tsis zoo nrog cov phooj ywg, thiab kev ua haujlwm tsis zoo hauv zej zog. Kev tshawb fawb tau qhia tias cov menyuam yaus uas muaj ADHD muaj cov kua qaub nervonic qis dua hauv lawv cov ntshav piv rau cov menyuam yaus ib txwm. Kev tshawb fawb qhia tias kev noj cov kua qaub nervonic txaus tuaj yeem txhim kho cov tsos mob ADHD thiab kev tsom mus rau cov menyuam yaus.

Txo Qhov Kev Pheej Hmoo ntawm Alzheimer's, Psychosis, thiab Depression

Kev tshuaj xyuas ntawm 260 tus neeg laus uas muaj teeb meem kev paub thiab lawv cov roj fatty acid hauv cov ntshav tau qhia txog kev pheej hmoo tsawg dua ntawm tus kab mob Alzheimer (AD) nrog cov qib siab dua ntawm ob qho tib si nervonic acid thiab DHA. Tsis tas li ntawd, kev sim tau qhia tias cov roj noob maple uas muaj nervonic acid tuaj yeem ua kom BDNF / TrkB signaling pathway, ua rau muaj kev qhia tawm ntawm cov protein postsynaptic PSD95, GluA1, thiab NMDAR1, thiab txo cov mRNA ntawm cov yam ntxwv inflammatory IL-1β, TNFα, thiab IL-6, yog li ua rau txo qis kev tsis muaj zog ntawm lub paj hlwb thiab txhim kho kev nco hauv cov neeg laus.
Lwm cov kev tshawb fawb tau txuas cov qib qis ntawm cov kua qaub nervonic rau cov tsos mob prodromal ntawm kev puas siab puas ntsws thiab kev nyuaj siab. Kev tshawb fawb qhia tias kev noj cov kua qaub nervonic txaus tuaj yeem txo qhov kev pheej hmoo ntawm Alzheimer's, kev puas siab puas ntsws, thiab kev nyuaj siab.

Txhawb kev kho Myelin

Cov kev sim ntawm cov nas uas noj roj noob maple uas muaj nervonic acid ua rau cov hlwb demyelination ploj mus tau qhia tias cov nas no yuav luag zoo rov qab mus rau qib pawg tswj hwm. Lwm cov kev tshawb fawb tau qhia tias kev noj zaub mov ntxiv nrog nervonic acid tuaj yeem txhim kho kev loj hlob thiab kev rov ua dua tshiab ntawm oligodendrocytes.

Txo Qhov Kev Pheej Hmoo ntawm Kab Mob Plawv

Cov kev tshawb fawb tau pom tias cov kua qaub nervonic tuaj yeem txo qhov kev pheej hmoo ntawm kev mob stroke ischemic. Cov laj thawj suav nrog:
Kho thiab tshem tawm cov hlab ntsha hauv lub hlwb uas puas lawm
Rov ua kom cov hlab ntsha ua haujlwm zoo dua qub
Txhawb kev tsim cov hlwb tshiab
Tiv thaiv kev laus ntawm cov hlab ntsha hauv lub hlwb
Kho thiab kho cov phab ntsa uas laus, puas lawm, thiab tawv ntawm lub plawv thiab cov hlab ntsha
Kev hloov kho cov ntaub so ntswg ntawm phab ntsa vascular
Rov qab kho qhov elasticity thiab lub zog ntawm cov hlab ntsha

IV. Cov menyuam mos puas noj tau Nervonic Acid? Thaum twg lawv yuav tsum pib noj tshuaj ntxiv?

Cov lus teb yeej yooj yim to taub. Cia peb los saib cov kev ntsuam xyuas ntawm cov chaw haujlwm hauv tebchaws thiab thoob ntiaj teb, nrog rau cov cai tswjfwm zaub mov.

1. Cov Cai ntawm FDA

Raws li cov ntaub ntawv FDA raug cai, cov kua qaub nervonic uas tau los ntawm cov tshuaj sib xyaw ua ke tuaj yeem siv ua tshuaj.
Rau kev kho mob cov kab mob xws li isovaleric acidemia, qhov ntau npaum li cas yog 200-300mg.

Txawm li cas los xij, FDA tsis tau lees paub tias nervonic acid los ntawm lwm qhov chaw siv rau hauv cov mis mos rau menyuam yaus. Raws li FDA cov cai, yog tias ib qho khoom xyaw yuav tsum siv rau hauv cov mis mos rau menyuam yaus, nws yuav tsum tau lees paub tias Generally Recognized as Safe (GRAS) los ntawm US FDA rau cov mis mos rau menyuam yaus. Nervonic acid meej meej tsis ua raws li qhov qauv no.

2. Cov Cai ntawm EU

EU tsis tau tshuaj xyuas ncaj qha rau nervonic acid, yog li tsis muaj cov ntaub ntawv tseem ceeb.

3. Cov Cai Suav

Thaum ntxov li Lub Peb Hlis 22, 2011, Lub Tsev Haujlwm Saib Xyuas Kev Noj Qab Haus Huv tau tshaj tawm ib daim ntawv tshaj tawm tias cov roj noob maple tau dhau qhov kev tshaj tawm zaub mov tshiab.

Ua ke cov cai thiab nug cov ntsiab lus ntawm nervonic acid hauv cov roj noob maple, nws pom tias cov roj noob maple feem ntau muaj 3% -5% nervonic acid. Raws li cov cai tshiab ntawm cov khoom noj khoom haus, qhov kev txwv txhua hnub ntawm nervonic acid yog kwv yees li 150mg.
Raws li tau hais ua ntej lawm, lub npe tshuaj ntawm nervonic acid yog cis-15-tetracosenoic acid. Xyoo 2017, Pawg Neeg Saib Xyuas Kev Noj Qab Haus Huv thiab Tsev Neeg tau tshaj tawm lwm cov lus tshaj tawm tshiab txog cov khoom noj khoom haus nervonic acid uas tau los ntawm roj rapeseed.

Daim ntawv tshaj tawm no tau hais meej meej tias cov menyuam mos yuav tsum tsis txhob noj cov khoom no, thiab yog tias cov khoom siv ncaj qha rau cov tshuaj no, daim ntawv lo yuav tsum qhia tias nws tsis haum rau cov menyuam mos.

Raws li cov cai tam sim no, txawm tias cov kua qaub nervonic yog los ntawm cov tshuaj lossis cov khoom noj, nws tsis haum rau cov menyuam mos. Ntau tus neeg yuav nug tias, "Tab sis yog tias mis niam muaj nws, vim li cas peb thiaj siv tsis tau?" Qhov no muaj ob yam. Ua ntej, tam sim no muaj kev tshawb fawb tsawg txog kev nyab xeeb ntawm cov kua qaub nervonic rau cov menyuam mos, thiab nws tsis tau siv dav thoob ntiaj teb. Xav tau kev tshawb fawb ntxiv. Qhov thib ob, seb cov menyuam mos puas xav tau ntxiv cov kua qaub nervonic kuj yog ib lo lus nug uas tsis muaj kev tshawb fawb txaus. Tam sim no tsis muaj cov ntaub ntawv tseem ceeb los ua pov thawj tias cov menyuam mos tsis muaj kua qaub nervonic txaus. Yog li ntawd, xav tau kev tshawb fawb ntxiv kom paub meej qhov no.

Yog li ntawd, raws li cov cai thiab kev ntsuam xyuas tam sim no, nws raug pom zoo kom pib ntxiv nrog nervonic acid thaum muaj hnub nyoog 3 xyoos lossis laus dua. Ntau tus niam txiv yuav xav tias xis nyob dua yog tias lawv ntxiv cov menyuam mos hnub nyoog qis dua 3 xyoos. Hauv cov xwm txheej zoo li no, kev ntxiv zaub mov raug pom zoo.

Yuav rov hais dua, tsis muaj pov thawj txaus los txhawb kev ntxiv cov kua qaub nervonic rau cov menyuam mos. Los ntawm kev kho mob thiab kev noj haus, tsis muaj cov ntaub ntawv qhia tias kev ntxiv yog qhov tsim nyog. Yog li ntawd, nws raug pom zoo kom siv txoj hauv kev zoo los ntxiv cov kua qaub nervonic rau cov menyuam mos.

Txawm hais tias txhua tus niam txiv xav kom muaj ib tug menyuam ntse, nws raug nquahu kom tsom mus rau kev noj zaub mov zoo thaum siv sijhawm ntau dua nrog koj tus menyuam, muab ib puag ncig zoo rau kev nyob, thiab txhawb kom muaj kev ua ub ua no sab nraum zoov. Cov yam no feem ntau tseem ceeb dua.