Xov Xwm - Puas Yog Licorice Extract Glabridin Ua Haujlwm Tiag?

I. Kev Taw Qhia

Kev lag luam saib xyuas tawv nqaij tau qhuas qhov kev ua kom dawb ntawm "Glabridin"(rho tawm ntawm Glycyrrhiza glabra) vim nws dhau qhov ua kom dawb arbutin los ntawm 1164 zaug, khwv tau lub npe hu ua "kub dawb"! Tab sis puas yog nws yeej zoo kawg li nws lub suab? Nws ua li cas thiaj ua tiav cov txiaj ntsig zoo kawg li no?

Thaum lub caij hloov pauv thiab txoj kev tau zoo nkauj nrog ntau "ob txhais ceg liab qab thiab caj npab liab qab," lub ntsiab lus ntawm kev sib tham ntawm cov neeg nyiam kev zoo nkauj, tsis suav nrog kev tiv thaiv hnub, yeej ib txwm tig mus rau kev ua kom tawv nqaij dawb.

Hauv kev saib xyuas daim tawv nqaij, muaj ntau yam khoom xyaw ua kom dawb, suav nrog vitamin C, niacinamide, arbutin, hydroquinone, kojic acid, tranexamic acid, glutathione, ferulic acid, phenethylresorcinol (377), thiab ntau ntxiv. Txawm li cas los xij, cov khoom xyaw "glabridin" tau ua rau ntau tus kiv cua xav paub ntxiv, ua rau muaj kev tshawb nrhiav tob tob kom pom nws qhov nrov zuj zus. Cia peb kawm txog cov ntsiab lus!

Los ntawm tsab xov xwm no, peb lub hom phiaj yog los hais txog cov ntsiab lus tseem ceeb hauv qab no:
(1) Glabridin keeb kwm yog dab tsi? Nws muaj feem cuam tshuam li cas rau "Glycyrrhiza glabra extract"?
(2) Vim li cas "Glabridin" thiaj li raug hwm tias yog "kub dawb"?
(3) Cov txiaj ntsig ntawm "Glabridin" yog dab tsi?
(4) Glabridin ua tiav nws cov teebmeem dawb li cas?
(5) Puas yog licorice muaj zog tiag tiag li tau hais?
(6) Cov khoom siv tu tawv nqaij twg muaj Glabridin?

No.1 Qhia Txog Keeb Kwm ntawm "Glabridin"

Glabridin, yog ib tug tswv cuab ntawm tsev neeg licorice flavonoid, yog muab los ntawm cov nroj tsuag "Glycyrrhiza glabra." Hauv kuv lub tebchaws, muaj yim hom licorice tseem ceeb, nrog rau peb hom suav nrog hauv "Pharmacopoeia," uas yog Ural licorice, licorice bulge, thiab licorice glabra. Glycyrrhizin tsuas pom muaj nyob rau hauv Glycyrrhiza glabra, ua haujlwm ua lub ntsiab isoflavone Cheebtsam ntawm cov nroj tsuag.

Cov qauv ntawm glycyrrhizin
Chiv thawj, lub tuam txhab Nyiv Pooj MARUZEN tau tshawb pom thiab rho tawm los ntawm Glycyrrhiza glabra, glycyrrhizin tau siv dav ua ib qho khoom ntxiv rau hauv cov khoom siv ua kom tawv nqaij dawb thoob plaws Nyiv Pooj, Kauslim Teb, thiab ntau lub npe nrov thoob ntiaj teb. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias cov khoom xyaw uas teev nyob rau hauv cov khoom siv ua kom tawv nqaij uas peb siv yuav tsis yog "glycyrrhizin" tab sis yog "Glycyrrhiza extract." Txawm hais tias "Glycyrrhizin" yog ib yam khoom tshwj xeeb, "Glycyrrhiza extract" tej zaum yuav muaj cov khoom ntxiv uas tsis tau raug cais tawm thiab ntxuav tag nrho, tej zaum yuav ua haujlwm ua ib qho kev lag luam los qhia txog cov yam ntxwv "ntuj".

No.2 Vim li cas licorice thiaj hu ua "Kub Dawb"?

Glycyrrhizin yog ib yam khoom xyaw uas tsis tshua muaj thiab nyuaj rau rho tawm. Glycyrrhiza glabra tsis yooj yim nrhiav tau ntau. Ua ke nrog qhov nyuaj ntawm cov txheej txheem rho tawm, tsawg dua 100 grams tuaj yeem tau los ntawm 1 tuj ntawm cov qia thiab nplooj licorice tshiab. Qhov tsis txaus no ua rau nws muaj nqis, ua rau nws yog ib qho ntawm cov khoom siv raw kim tshaj plaws hauv cov khoom siv tawv nqaij, piv rau kub. Tus nqi ntawm 90% cov khoom siv raw ntshiab ntawm cov khoom xyaw no nce mus txog ntau dua 200,000 yuan / kg.
Kuv xav tsis thoob, yog li kuv mus saib lub vev xaib Aladdin kom paub meej ntxiv. Cov tshuaj ntsuab licorice uas tau txheeb xyuas tias huv (purity ≥99%) raug muag rau tus nqi tshaj tawm ntawm 780 yuan / 20mg, sib npaug rau 39,000 yuan / g.
Tam sim ntawd, kuv tau txais kev hwm tshiab rau cov khoom xyaw yooj yim no. Nws cov nyhuv ua kom dawb zoo tshaj plaws tau ua rau nws tau txais lub npe hu ua "kub ua kom dawb" lossis "Kub Dawb".

No.3 Lub luag haujlwm ntawm Glabridin yog dab tsi?

Glabridin muaj ntau yam khoom siv hauv lub cev. Nws ua haujlwm ua ib qho khoom xyaw zoo, muaj kev nyab xeeb, thiab zoo rau ib puag ncig rau kev ua kom dawb thiab tshem tawm cov quav hnav. Tsis tas li ntawd, nws muaj cov tshuaj tua kab mob, tiv thaiv kev o, antioxidant, tiv thaiv kev laus, thiab tiv thaiv ultraviolet. Nws cov txiaj ntsig zoo hauv kev ua kom dawb, ci, thiab tshem tawm cov quav hnav tau txhawb nqa los ntawm cov ntaub ntawv sim, uas qhia tau tias cov txiaj ntsig dawb ntawm Glabridin ntau dua li vitamin C ntau dua 230 npaug, hydroquinone ntau dua 16 npaug, thiab tus neeg sawv cev ua kom dawb nto moo arbutin ntau dua 1164 npaug.

No.4 Lub tshuab ua kom dawb ntawm glabridin yog dab tsi?

Thaum daim tawv nqaij raug rau cov teeb ultraviolet, ua rau muaj cov free radicals, melanocytes raug txhawb kom tsim tyrosinase. Nyob rau hauv kev cuam tshuam ntawm cov enzyme no, tyrosine hauv daim tawv nqaij tsim melanin, ua rau daim tawv nqaij tsaus ntuj thaum melanin raug thauj los ntawm txheej basal mus rau stratum corneum.
Lub hauv paus ntsiab lus ntawm txhua yam khoom xyaw ua kom dawb yog cuam tshuam rau hauv cov txheej txheem ntawm kev tsim melanin lossis kev thauj mus los. Glabridin lub tshuab ua kom dawb feem ntau suav nrog peb yam hauv qab no:
(1) Kev txwv tsis pub ua tyrosinase
Glabridin qhia tau tias muaj zog tiv thaiv kev ua haujlwm ntawm tyrosinase, ua rau pom tseeb thiab tseem ceeb. Kev sim ua hauv computer qhia tau tias glabridin tuaj yeem khi rau qhov chaw ua haujlwm ntawm tyrosinase los ntawm cov hydrogen bonds, thaiv kev nkag mus ntawm cov khoom siv raw rau kev tsim melanin (tyrosine), yog li ntawd cuam tshuam kev tsim melanin. Txoj hauv kev no, hu ua kev txwv tsis pub sib tw, zoo ib yam li kev ua siab loj.

(2) Tiv thaiv kev tsim cov tshuaj reactive oxygen (antioxidant)
Kev raug rau cov teeb ultraviolet ua rau muaj cov tshuaj reactive oxygen (cov free radicals), uas tuaj yeem ua rau daim tawv nqaij puas tsuaj, ua rau erythema thiab pigmentation. Yog li ntawd, cov tshuaj reactive oxygen paub tias pab txhawb rau cov tawv nqaij pigmentation, qhia txog qhov tseem ceeb ntawm kev tiv thaiv hnub hauv kev saib xyuas tawv nqaij. Cov kev tshawb fawb sim tau qhia tias glabridin muaj peev xwm tshem tawm cov free radical zoo sib xws rau superoxide dismutase (SOD), ua haujlwm ua antioxidant. Qhov no pab txo cov yam tseem ceeb uas ua rau muaj kev ua haujlwm tyrosinase ntau ntxiv.

(3) Tiv thaiv kev o
Tom qab daim tawv nqaij raug mob los ntawm cov teeb ultraviolet, qhov tshwm sim ntawm erythema thiab pigmentation yog nrog los ntawm kev o, ntxiv ua rau melanin ntau ntxiv thiab ua rau lub voj voog tsis zoo. Glabridin cov khoom tiv thaiv kev o tsim ib puag ncig zoo rau kev tiv thaiv melanin tsim rau qee qhov, thaum tseem txhawb kev kho cov tawv nqaij puas tsuaj.

No. 5 Puas Yog Glabridin Muaj Zog Tiag?

Glabridin tau raug qhuas tias yog ib qho khoom xyaw zoo thiab zoo rau ib puag ncig rau kev ua kom dawb thiab tshem tawm cov quav hnav, khav txog lub tshuab ua kom dawb zoo thiab muaj txiaj ntsig zoo kawg. Cov ntaub ntawv sim qhia tias nws cov txiaj ntsig ua kom dawb zoo dua li "whitening giant" arbutin ntau dua ib txhiab npaug (raws li tau tshaj tawm hauv cov ntaub ntawv sim).
Cov kws tshawb nrhiav tau ua ib qho qauv sim tsiaj siv zebrafish los ntsuas qhov cuam tshuam ntawm glabridin rau melanin, qhia txog kev sib piv tseem ceeb nrog kojic acid thiab bearberry.
Ntxiv rau kev sim tsiaj, cov txiaj ntsig kho mob kuj tseem qhia txog qhov ua kom dawb ntawm glabridin, nrog rau cov txiaj ntsig pom tseeb pom hauv 4-8 lub lis piam.
Txawm hais tias qhov ua tau zoo ntawm cov khoom xyaw ua kom dawb no pom tseeb, nws txoj kev siv tsis dav npaum li lwm cov khoom xyaw ua kom dawb. Hauv kuv lub tswv yim, qhov laj thawj tseem ceeb yog nws "qhov xwm txheej kub" hauv kev lag luam - nws kim heev! Txawm li cas los xij, tom qab siv cov khoom siv saib xyuas tawv nqaij uas siv ntau dua, muaj kev loj hlob ntawm cov tib neeg nrhiav cov khoom uas muaj cov khoom xyaw "kub" no.

No.6 Cov Khoom Siv Tawv Nqaij Twg Muaj Glabridin?

Lus Ceeb Toom: Cov hauv qab no yog daim ntawv teev npe, tsis yog lus pom zoo!
Glabridin yog ib yam khoom xyaw muaj zog rau kev saib xyuas tawv nqaij uas paub txog nws cov yam ntxwv ua rau tawv nqaij ci ntsa iab. Nws tuaj yeem pom muaj nyob rau hauv ntau yam khoom siv saib xyuas tawv nqaij, suav nrog cov serums, essences, lotions, thiab masks. Qee yam khoom tshwj xeeb uas yuav muaj Glabridin, txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias qhov muaj Glabridin nyob rau hauv cov khoom siv saib xyuas tawv nqaij yuav txawv, thiab nws yog ib qho tseem ceeb kom ua tib zoo saib cov npe khoom xyaw ntawm cov khoom tshwj xeeb kom paub tias nws muaj nyob hauv.
(1) Aleble Licorice Queen Tshuaj Pleev Lub Cev
Daim ntawv teev cov khoom xyaw tseem ceeb muaj "Glycyrrhiza glabra" ua cov khoom xyaw thib ob (tom qab dej), nrog rau glycerin, sodium hyaluronate, squalane, ceramide, thiab lwm yam khoom xyaw moisturizing.
(2) Cov Khoom Siv Pleev Xim Rau Menyuam Yaus, Txiv Hmab Txiv Ntoo, Licorice, thiab Dej Kho Kom Zoo Nkauj
Cov khoom xyaw tseem ceeb suav nrog Glycyrrhiza glabra extract, hydrolyzed algae extract, arbutin, Polygonum cuspidatum cag extract, Scutellaria baicalensis cag extract, thiab ntau ntxiv.
(3) Kokoskin Snow Clock Essence Body Serum
Muaj 5% nicotinamide, 377, thiab glabridin ua nws cov khoom tseem ceeb.
(4) Lub Npog Ncauj Licorice (Ntau Hom)
Cov khoom no sib txawv, qee yam muaj tsawg kawg nkaus thiab muag raws li tshuaj ntsuab "glabragan."
(5) Guyu Licorice Series

No.7 Kev Tsim Txom Ntsuj Plig

(1) Puas yog Glabridin hauv cov khoom siv tawv nqaij tau rho tawm los ntawm licorice tiag?
Lo lus nug txog seb Glabridin hauv cov khoom siv rau kev saib xyuas tawv nqaij puas yog rho tawm los ntawm licorice yog qhov tseeb. Cov qauv tshuaj ntawm licorice extract, tshwj xeeb tshaj yog glabridin, yog qhov sib txawv, thiab cov txheej txheem rho tawm tuaj yeem kim heev. Qhov no tsa cov lus nug txog seb nws puas yuav siv tau zoo dua los xav txog kev tsim tshuaj lom neeg ua lwm txoj hauv kev rau kev tau txais glabridin. Thaum qee cov tshuaj, xws li artemisinin, tuaj yeem tau txais los ntawm kev tsim tag nrho, nws yog qhov ua tau los tsim glabridin thiab. Txawm li cas los xij, qhov cuam tshuam ntawm kev tsim tshuaj lom neeg piv rau kev rho tawm yuav tsum tau txiav txim siab. Tsis tas li ntawd, tej zaum yuav muaj kev txhawj xeeb txog kev siv lub npe "Glycyrrhiza glabra extract" hauv cov npe khoom xyaw ntawm cov khoom siv rau kev saib xyuas tawv nqaij kom tsim kom muaj kev thov lag luam khoom xyaw ntuj. Nws yog ib qho tseem ceeb kom nkag mus rau hauv keeb kwm thiab cov txheej txheem tsim khoom ntawm cov khoom xyaw rau kev saib xyuas tawv nqaij kom ntseeg tau tias muaj kev pom tseeb thiab qhov tseeb.

(2) Kuv puas siv tau cov tshuaj licorice uas muaj cov tshuaj dawb huv ncaj qha rau ntawm kuv lub ntsej muag kom tau daim tawv nqaij dawb zoo li daus?
Cov lus teb yog tsis yog kiag li! Txawm hais tias qhov ua kom dawb ntawm glabridin yog qhov zoo, nws cov khoom txwv nws txoj kev siv ncaj qha. Glycyrrhizin yuav luag tsis yaj hauv dej, thiab nws lub peev xwm nkag mus rau hauv daim tawv nqaij tsis muaj zog. Kev koom ua ke nws rau hauv cov khoom siv tawv nqaij yuav tsum muaj cov txheej txheem tsim khoom thiab npaj khoom hnyav. Yog tsis muaj cov qauv zoo, nws yuav nyuaj rau ua tiav qhov txiaj ntsig xav tau. Txawm li cas los xij, kev tshawb fawb tau ua rau muaj kev tsim cov tshuaj pleev ib ce hauv daim ntawv ntawm liposomes, txhim kho kev nqus thiab kev siv glabridin los ntawm daim tawv nqaij.

cov ntaub ntawv siv:
[1] Pigmentation: dyschromia [M]. Thierry Passeron thiab Jean-Paul Ortonne, 2010.
[2] J. Chen et al. / Spectrochimica Acta Tshooj A: Molecular thiab Biomolecular Spectroscopy 168 (2016) 111–117