I. Kev qhia lus
PhospholipidsYog cov khoom tseem ceeb ntawm cov roj ntsha thiab cov cwj pwm tseem ceeb hauv ntau cov txheej txheem physiological. Nkag siab txog lawv cov qauv thiab kev ua haujlwm yog kev nkag siab ntawm kev nyuaj ntawm kev noj qab haus huv ntawm kev noj qab haus huv ntawm tib neeg thiab kab mob. Qhov kev nthuav dav no txheej txheem txheej txheem rau relve mus rau hauv intricate xwm ntawm phospholipids, zoo li qhia txog qhov tseem ceeb ntawm kev kawm cov molecules no.
A. Kev Txhais thiab Qauv ntawm Phospholipids
Phospholipids yog chav kawm lipids uas muaj ob pab tsiaj ua ke, ib pab pawg phosphot, thiab glycerol caj qaum. Tus qauv ntawm phospholipipids ua rau lawv ua lipid bilayer, nrog hydrophobic tails tig sab hauv thiab hydrophilic taub hau tig mus sab nraud. Qhov kev npaj no muab cov kev thaiv kev sib xyaw ua ke uas tswj cov tshuaj ntawm cov khoom hauv thiab tawm ntawm lub xov tooj, txawm tias muaj ntau yam kev ua haujlwm ntawm tes hluav taws xob xws li kev kos npe thiab thauj.
B. Qhov tseem ceeb ntawm kev kawm phospholipids
Kawm phospholipids yog qhov tseem ceeb rau ntau yam. Firstly, lawv yog qhov tseem ceeb rau cov qauv thiab kev ua haujlwm ntawm cov xovtooj ntawm tes, cuam tshuam rau membrane fluidity, permeability, thiab ruaj khov. Nkag siab txog cov khoom ntawm phospholipids yog qhov tseem ceeb rau unraving cov txheej txheem xws li cov txheej txheem cellular
Ntxiv mus, phospholipids muaj qhov cuam tshuam tseem ceeb rau tib neeg kev noj qab haus huv, tshwj xeeb txog cov mob xws li mob plawv, neurodegenerative kev tsis sib haum xeeb, thiab metabolic syndromes. Kev Tshawb Fawb Txog Phospholipids tuaj yeem muab cov kev nkag siab rau hauv kev txhim kho ntawm kev xav tshiab kho cov tswv yim thiab kev noj haus cuam cuam tshuam cov teeb meem kev noj qab haus huv.
Tsis tas li ntawd, kev lag luam thiab cov ntawv thov ua lag luam ntawm cov chaw xws li cov tshuaj, cov khoom siv biotechnology, thiab biotechnology biotechnology, thiab biotechnology inderscore qhov tseem ceeb ntawm kev vam meej ntawm peb txoj kev paub hauv daim teb no. Nkag siab txog ntau lub luag haujlwm thiab cov khoom ntawm phospholipids tuaj yeem ua rau kev txhim kho cov khoom lag luam tshiab thiab kev ua haujlwm dav dav rau tib neeg kev noj qab haus huv thiab thev naus laus zis.
Hauv cov ntsiab lus, kev kawm ntawm phospholipids yog qhov tseem ceeb rau untricate cov qauv kev kawm thiab muaj nuj nqi rau tib neeg kev noj qab haus huv, thiab harnessing lawv muaj peev xwm hauv ntau hom kev lag luam. Qhov kev nthuav dav no ua rau pom lub teeb pom kev zoo ntawm phospholipids thiab lawv qhov tseem ceeb hauv kev tshawb fawb txog cov roj ntsha, tib neeg txoj kev nyab xeeb, thiab thev naus laus zis thev naus laus zis.
Ii. Kev Ua Haujlwm Biological ntawm Phospholipids
Phospholipids, ib qho tseem ceeb ntawm cell week, ua si ntau lub luag haujlwm hauv kev tswj hwm cov qauv cellular thiab kev cuam tshuam ntau yam kev cuam tshuam ntawm cov txheej txheem muaj sia. Nkag siab txog cov haujlwm phospholipids tau pom txog lawv qhov tseem ceeb hauv tib neeg kev noj qab haus huv thiab kab mob.
A. Lub luag haujlwm hauv cell membrane qauv thiab muaj nuj nqi
Thawj biological muaj nuj nqi ntawm phospholipids yog lawv txoj kev koom tes rau cov qauv thiab kev ua haujlwm ntawm cov xovtooj ntawm tes. Phospholipids phospidids photpidids photpid bilayer, lub hom phiaj yooj yim ntawm cov ntaub qhwv cell, los ntawm kev npaj lawv tus kheej nrog lawv cov taub hau hydrophobic sab hauv. Cov qauv no tsim cov kab mob semipermeable uas tswj cov khoom seem ntawm cov khoom hauv xov tooj ntawm lub tsev kawm ntawv, kom muaj kev tswj hwm ntawm cov khoom noj muaj zog, khib nyiab, thiab phiajcim ntawm tes.
B. Kev sib txuas lus thiab kev sib txuas lus hauv cov hlwb
Phospholipids kuj tseem ua haujlwm tseem ceeb ntawm kev teeb tsa txoj hauv kev thiab kev sib txuas lus ntawm tes-rau-cell. Tej yam phospholipids, xws li phosphatidylinositol, ua raws li cov txheej txheem tseem ceeb rau kev loj hlob ntawm cov txheej txheem cellular, suav nrog kev loj hlob ntawm tes, suav nrog kev loj hlob ntawm tes, thiab muaj kev sib txawv. Cov phiajcim molecules no ua si cov luag hauj lwm tseem ceeb hauv kev piav qhia txog kev sib txawv thiab kev sib txawv ntawm cov lus teb hauv kev sib txawv thiab tus cwj pwm canular.
C. Muab kev pab rau lub hlwb thiab kev txawj ntse
Phospholipids, tshwj xeeb yog phosphatidylcholine, thiab phosphattidylserine, muaj ntau nyob rau hauv lub hlwb thiab yog qhov tseem ceeb rau kev tswj hwm nws cov qauv thiab muaj nuj nqi. Phospholipids pab txhawb rau qhov tsim thiab muaj kev ruaj ntseg ntawm neuroal cov tshuaj ntxuav, thiab cuam tshuam rau hauv synaptic plasticity, uas yog qhov tseem ceeb rau kev kawm thiab cim xeeb. Tsis tas li ntawd, phospholipids ua lub luag haujlwm hauv kev ua haujlwm hauv kev ua raws li kev txawj xav cuam tshuam nrog kev laus thiab kev ua haujlwm ntawm neurological.
D. Kev cuam tshuam rau kev noj qab haus huv thiab plawv plawv
Phospholipids tau ua kom pom cov kev cuam tshuam tseem ceeb rau lub plawv kev noj qab haus huv thiab kev mob plawv. Lawv koom nrog hauv cov qauv thiab cov haujlwm ntawm cov lipoproteins, uas thauj cov roj thiab lwm yam lipids hauv cov hlab ntshav. Phospholipids nyob rau hauv lipoproteins pab rau lawv ruaj ntseg thiab muaj nuj nqi, muaj peev xwm ua haujlwm lipid metabolism thiab cholesterol thundostasis. Ib qho ntxiv, phospholipids tau kawm rau lawv lub peev xwm los hloov cov ntshav lipid cov lus qhia thiab txo lawv cov peev xwm kho tau qhov cuam tshuam hauv kev tswj hwm lub plawv.
E. Kev Koom Tes Hauv Lipid Metabolism thiab Zog Ntau Lawm
Phospholipids yog qhov tseem ceeb rau Lipid metabolism thiab kev tsim hluav taws xob. Lawv koom nrog synthesis thiab rhuav tshem lipids, suav nrog triglycerides thiab cov roj (cholesterol), thiab ua si txoj haujlwm tseem ceeb hauv lipid thauj thiab cia. Phospholipids kuj tseem ua rau mitochondrial muaj nuj nqi thiab kev sib koom tes hluav taws xob, tsis muaj qhov tseem ceeb hauv lub zog metabolism.
Hauv cov ntsiab lus, cov khoom siv roj ntsha ntawm phospholipids tau muaj ntau yam thiab kev sib txuas lus hauv lub hlwb thiab kev sib raug zoo hauv Lipid metabolism thiab kev sib koom tes. Qhov kev sib tham no ua rau muaj kev nkag siab tob txog kev sib txawv ntawm cov phospholips thiab lawv cuam tshuam rau tib neeg kev noj qab haus huv thiab kev noj qab haus huv.
III. Cov txiaj ntsig kev noj qab haus huv ntawm phospholipids
Phospholipids yog qhov tseem ceeb ntawm cov xov xwm ntawm tes ntawm cov haujlwm hauv tib neeg kev noj qab haus huv. To taub cov txiaj ntsig kev noj qab haus huv ntawm Phospholipids tuaj yeem tsim lub teeb ntawm lawv cov ntawv thov kev noj haus muaj peev xwm kho tau.
Cuam tshuam ntawm cov qib roj (cholesterol)
Phospholipids ua si lub luag haujlwm tseem ceeb hauv Lipid metabolism thiab thauj, uas ncaj qha cuam tshuam cov roj cholesol rau hauv lub cev. Kev tshawb fawb tau pom tias phospholipids tuaj yeem coj cov roj metabolism los ntawm kev cuam tshuam cov synthesis, kev nqus, thiab kev ua haujlwm ntawm cov roj (cholesterol). Phospholipids tau tshaj tawm tias muaj kev pab hauv emulsification thiab solubilization ntawm kev ua noj ua rog, yog li pab txhawb kev nqus cov roj (cholesterol). Ib qho ntxiv, phospholipids muaj kev koom tes nrog kev tsim ntawm cov roj av siab (HDL), uas tau pom tias muaj kev pheej hmoo ntawm cov ntshav hauv aferosclerosis thiab cov kab mob plawv. Cov ntaub ntawv pov thawj qhia tias Phospholipids yuav muaj peev xwm txhim kho cov nkauj ntxig roj thiab pab txhawb rau cov qib roj noj kom zoo ntawm cov roj (cholesterol) hauv lub cev.
Antioxidative cov khoom
Phospholipids pom cov khoom tiv thaiv kab mob antioxidative uas ua rau lawv muaj txiaj ntsig zoo rau kev noj qab haus huv. Raws li kev sib xyaw ua ke ntawm cov tshuaj caug cellular, phospholipids muaj kev puas tsuaj oxidative thiab reactive oxygen hom. Txawm li cas los xij, phospholipids muaj cov peev xwm antioxident muaj peev xwm, ua raws li cov kiav txhab dawb thiab tiv thaiv cov hlwb los ntawm oxidative kev ntxhov siab. Cov kev tshawb fawb tau pom tias cov phospholipmipids tshwj xeeb, xws li phosphatidylchology thiab tuaj yeem ua kom muaj kev puas tsuaj oxidating thiab tiv thaiv lipid peroxidation. Tsis tas li ntawd, phospholipids tau cuam tshuam rau kev txhim kho lub kab mob antioxidant kev tiv thaiv kab mob tsis pub dhau cov kev tiv thaiv oxidative thiab cov patholidative.
Tej zaum yuav kho cov ntaub ntawv thov thiab khoom noj khoom haus
Cov txiaj ntsig kev noj qab haus huv tshwj xeeb ntawm phospholipids tau tsim kev txaus siab rau lawv cov kev siv khoom noj muaj peev xwm. Phospholipid-raws li kev kho mob raug tshawb xyuas rau lawv lub peev xwm hauv kev tswj cov lipid-cuam tshuam tsis zoo, xws li hypercholes thiab dyslipidemia. Tsis tas li ntawd, Phospholipids tau qhia cov lus cog lus hauv kev txhawb nqa daim siab muaj zog thiab txhawb nqa Lepatic Lipid metabolism thiab kev ntxhov siab oxidative. Cov zaub mov noj ntawm cov zaub mov phospholipids tau pom nyob rau hauv lub realm cov zaub mov thiab kev noj haus huv, txhawb kev noj qab haus huv ntawm kev noj qab haus huv, thiab txhawb nqa kev noj qab haus huv.
Hauv kev xaus, cov txiaj ntsig kev noj qab haus huv ntawm phospholipids encompass encompass lub zog, thiab lawv cov khoom noj khoom haus tshuaj thiab khoom noj muaj peev xwm kho tau. Nkag siab lub luag haujlwm ntau ntawm phospholipids nyob rau hauv kev saib xyuas lub tsev pheeb suab ntawm lub tsev ntawm kev pheej hmoo muab rau hauv lawv qhov tseem ceeb hauv kev txhawb nqa tib neeg kev noj qab haus huv thiab kev noj qab haus huv.
IV. Qhov chaw ntawm phospholipids
Phospholipids, zoo li kev ncaj ncees laspid cov cheebtsam ntawm cov tshuaj pwm cellular, yog qhov tseem ceeb rau kev tswj cov qauv txheej txheem kev ntseeg siab thiab ua haujlwm ntawm cov hlwb. Nkag siab txog cov peev txheej ntawm phospholipids yog qhov tseem ceeb rau kev txaus siab rau lawv qhov tseem ceeb hauv kev siv khoom noj khoom haus thiab kev lag luam.
A. Kev noj haus cov khoom noj
Cov Khoom Noj Khoom Noj: Pospholipids tuaj yeem tau txais los ntawm ntau cov kev noj haus cov khoom noj yog qe qe, khoom noj khoom haus, thiab taum pauv. Qe yolks tshwj xeeb muaj txiaj ntsig tshwj xeeb hauv phosphatidylcholine, ib hom phosphotidid, thaum ua kua phosphaterylserine thiab phosphatidylinositol. Lwm cov kev noj haus cov khoom noj ntawm phospholipids suav nrog cov khoom noj siv mis, txiv laum huab xeeb, thiab cov noob paj noob hlis.
Kev muaj mob biological: kev noj haus phospholipids yog qhov tseem ceeb rau tib neeg khoom noj thiab ua si tus qauv tseem ceeb hauv ntau yam txheej txheem siv dag. Thaum noj, phospholipids yog zom thiab nqus tau cov hnyuv me, uas lawv tau ua haujlwm ntawm cov lipoprotein hais tias cov roj (cholesterol) thiab triglycerides.
Kev tshawb nrhiav kev noj qab haus huv: Kev tshawb fawb tau pom tias kev noj zaub mov zoo, suav nrog kev noj qab haus huv lub hlwb, thiab ua rau muaj kev noj qab haus huv lub plawv. Ntxiv mus, phospholipids muab tau los ntawm cov roj av, xws li cov roj Krill, tau txais cov xim rau lawv cov peev xwm tiv thaiv thiab cov tshuaj tiv thaiv kab mob antioxidant thiab antioxidant.
B. Kev lag luam thiab cov khoom siv tshuaj
Muaj Extraction: phospholipids kuj tseem tau los ntawm kev muaj chaw, uas lawv tau rho tawm los ntawm ntuj cov ntaub ntawv nyoos xws li taum pauv, thiab rapiseds. Cov phospholipids no yog tom qab ntawd ua tiav thiab siv nyob rau hauv ntau cov ntawv thov, suav nrog kev siv emulsifiers, nrog cov neeg sawv cev ua haujlwm, thiab encapsultulation rau zaub mov, thiab kev lag luam kom hniav.
Cov ntawv thov tshuaj: Phospholipids ua lub luag haujlwm tseem ceeb hauv kev lag luam kws tshuaj, tshwj xeeb hauv kev siv tshuaj. Lawv tau siv los ua kom muaj kev zam rau hauv cov qauv ntawm lipid-raws li cov tshuab tshuaj khib nyiab los txhim kho cov xyoob ntoo, kev ruaj khov, thiab hom phiaj ntawm cov khoom sib txuas. Ib qho ntxiv, phospholipids tau tshawb nrhiav rau lawv lub peev xwm hauv kev tsim cov kws nqa tshuaj tshiab cov ntaub ntawv rau kev xa khoom thiab muaj kev tso tawm ntawm kev kho mob.
Tseem ceeb hauv kev lag luam: Cov ntawv thov kev lag luam ntawm phospholipids txuas ntxiv rau kev tsim khoom noj khoom haus, uas lawv ua emulsifiers thiab stabilizers hauv ntau cov zaub mov ua tiav. Phospholipids kuj tau siv rau hauv kev tsim cov kev saib xyuas tus kheej thiab cov khoom noj kom zoo nkauj, muaj kev ua kom zoo nkauj xws li cream, tshuaj, thiab liposomes.
Hauv kev xaus, phospholipids yog muaj los ntawm ob qho kev noj haus thiab kev lag luam, cov haujlwm tseem ceeb hauv cov khoom noj tib yam, kev noj qab haus huv, thiab ntau yam txheej txheem muaj. Nkag siab txog ntau qhov chaw thiab cov ntawv thov phospholipids yog qhov tseem ceeb rau kev txaus siab rau lawv qhov tseem ceeb hauv kev noj haus, kev noj qab haus huv, thiab kev lag luam.
V. Kev Tshawb Fawb thiab Kev Siv
A. Kev tshawb fawb tam sim no hauv Phospholipid
Kev tshawb fawb tam sim no hauv phospholipid Science muaj ntau hom ntawm cov ntsiab lus, thiab cov luag haujlwm ntawm phospholipids nyob rau hauv ntau cov txheej txheem roj lom. Cov ncauj lus tsis ntev los no suav nrog kev tshawb xyuas lub luag haujlwm tshwj xeeb uas cov chav kawm phospholipids sib txawv, membant metabolism, thiab Lipid metabolism. Ib qho ntxiv, muaj qhov tseem ceeb rau kev nkag siab txog kev hloov pauv ntawm phospholmids, nrog rau kev txhim kho cov tshuaj phospholip tshiab rau kev kawm phospholipids ntawm cov xov tooj ntawm tes thiab molecular.
B. Kev lag luam thiab cov ntaub ntawv thov tshuaj
Phospholipids tau pom ntau ntau kev muaj thiab cov ntaub ntawv thov siv tau vim lawv lub zog thiab tshuaj chemical. Hauv cov kev lag luam lag luam, phospholipids yog siv raws li emulsifiers, stabilizers, thiab encapsulating tus neeg sawv cev hauv cov zaub mov, kev lag luam kom zoo nkauj, thiab kev ua kom zoo nkauj. Hauv cov chaw kuaj tshuaj, phospholipids tau siv dav hauv cov tshuaj kho cov tshuaj, suav nrog cov qauv liposomes thiab lipid-raws li kev txhim kho solubility thiab bioavailability ntawm cov tshuaj. Kev siv phospholipipids hauv cov ntawv thov no tau nthuav dav lawv qhov cuam tshuam zoo rau ntau yam kev lag luam.
C. Yav Tom Ntej Cov Lus Qhia thiab cov nyom hauv Phospholipid Tshawb Fawb
Lub neej tom ntej ntawm Phospholipid kev tshawb fawb tau cog lus zoo, muaj cov ntaub ntawv zoo tshaj plaws xws li kev tshawb nrhiav ntawm phospholipipids. Cov kev cov nyom yuav cuam tshuam nrog cov teeb meem ntsig txog cov ntsuas pa, rov ua dua tshiab, thiab tus nqi tau zoo ntawm phospholipid-raws li cov khoom lag luam. Tsis tas li ntawd, nkag siab cov kev sib cuam tshuam ntawm phospholipids thiab lwm yam kev ua haujlwm ntawm lub cev, yuav yog ib thaj chaw tseem ceeb ntawm kev tshawb nrhiav ib ntus.
D.Phospholipid LiposomalCov khoom lag luam
Phospholipid Liposomal cov khoom yog qhov tseem ceeb ntawm kev ua kom pom tseeb hauv cov ntawv thov tshuaj. Liposomes, uas yog spherical vesicles muaj ntawm phospholipid bilayers, tau kawm ntau yam kev siv tshuaj. Cov khoom no muaj cov txiaj ntsig zoo xws li muaj peev xwm los encapsulate ob qho tshuaj hydrophobic, phiaj xwm tshwj xeeb cov nqaij, thiab txo qis kev phiv tshuaj ntawm qee yam tshuaj. Kev tshawb fawb txuas ntxiv thiab lub hom phiaj txhim kho txhawm rau txhim kho kev ruaj khov, tshuaj muaj peev xwm ntawm cov khoom siv phospholipid?
Qhov kev tshawb fawb thoob plaws qhov kev tshawb pom ntawm cov kab mob phosphibid, suav nrog cov khoom siv thiab cov khoom lag luam phospholipid-based. Qhov kev paub no hais txog cov kev tshwm sim ntau yam thiab cov cib fim cuam tshuam nrog phospholipids nyob rau hauv ntau thaj teb.
VI. Tag
A. Cov ntsiab lus ntawm Cov Tshawb Nrhiav Tseem Ceeb
Phospholipids, raws li qhov tseem ceeb ntawm cov roj ntsha ntawm cov roj ntsha, ua si cov haujlwm tseem ceeb hauv kev tswj hwm cov qauv cellular thiab muaj nuj nqi. Kev tshawb fawb tau qhia txog cov kav phospholipids nyob rau hauv phospholipids nyob rau hauv sellular signaling, membrane kev siv hluav taws xob, thiab lipid metabolism. Cov chav kawm phospholipip cov chav nyob tau pom muaj qhov sib txawv ntawm cov hlwb, muaj kev cuam tshuam cov txheej txheem xws li kev sib txawv ntawm tes, muaj kev cuam tshuam, thiab muaj mob. Tsis tas li ntawd, txoj kev sib txhawb paus ntawm Phospholipids, lwm yam lipids, thiab membrane proteins tau tawm los ntawm kev txiav txim siab ntawm cellular. Ib qho ntxiv, phospholipids muaj cov ntawv thov tseem ceeb, tshwj xeeb hauv kev tsim cov emulsifiers, stabilizers, thiab cov tshuaj me. To taub cov qauv thiab kev ua haujlwm ntawm phospholipids muab kev pom rau hauv lawv cov peev xwm kho thiab kev lag luam siv.
B. Kev siv rau kev noj qab haus huv thiab kev lag luam
Kev nkag siab txog phospholipipids muaj qhov cuam tshuam tseem ceeb rau ob qho kev lag luam thiab kev lag luam. Nyob rau hauv cov ntsiab lus ntawm kev noj qab haus huv, phospholipids yog qhov tseem ceeb rau kev tswj hwm kev ncaj ncees ntawm tes thiab muaj nuj nqi. Cov xwm txheej hauv PhospholipID tau cuam tshuam nrog ntau yam kab mob, suav nrog cov kab mob metabolic, neurodegenerative cov kab mob, thiab mob cancer. Yog li no, kev cuam tshuam kev cuam tshuam los hloov phospholipid metabolism thiab kev ua haujlwm yuav muaj peev xwm kho tau. Ntxiv mus, kev siv phospholipids muaj cov tshuab tshuaj muaj kev txhawb nqa txoj kev ua tau zoo thiab kev nyab xeeb ntawm cov tshuaj. Nyob rau hauv kev lag luam kheej, phospholipids yog qhov tseem ceeb rau kev tsim cov neeg siv khoom, suav nrog cov zaub mov emulsions, tshuaj pleev ib ce, thiab kws tshuaj pleev ib ce. To taub cov qauv kev sib raug zoo ntawm phospholipids tuaj yeem tsav tsheb tshiab, ua rau kev lag luam tshiab, ua rau kev txhim kho kev ruaj ntseg thiab cov khoom siv bioavailability.
C. Cov Sijhawm rau Kev Tshawb Fawb Ntxiv thiab Kev Loj Hlob
Kev tshawb fawb txuas ntxiv hauv phospholippocippocip Science nthuav qhia ntau txoj kev kom muaj kev tshawb nrhiav thiab kev txhim kho ntxiv. Ib thaj chaw tseem ceeb yog cov elucidation ntawm cov molecular txheej txheem rau kev koom tes ntawm phospholipids hauv phospholipids nyob rau hauv cov txheej txheem cellular thiab cov txheej txheem kab mob. Qhov kev paub no tuaj yeem siv tau los tsim cov phiaj xwm kev xav uas tau hloov kho cov metabolism phosolism rau cov txiaj ntsig kho. Ib qho ntxiv, kev tshawb xyuas ntxiv rau kev siv phospholipids raws li cov tsheb hloov tshuaj thiab kev txhim kho cov qauv laspid uas yog cov kws ua yeeb yam. Nyob rau hauv cov hauj lwm muaj, txuas ntxiv tshawb nrhiav thiab kev tsim kho ntawm kev ua haujlwm zoo thiab cov ntawv thov ntawm cov khoom lag luam ntawm cov neeg siv khoom. Ntxiv mus, tshawb txog kev siv thiab ib puag ncig tus phooj ywg ntawm phospholipids rau kev siv yog lwm thaj chaw tseem ceeb rau kev txhim kho.
Yog li, cov kev qhia dav dav ntawm phospholipid kev tshawb fawb tseem ceeb ntawm phospholipids qhov tseem ceeb ntawm kev noj qab haus huv, thiab lawv cov ntawv thov sib txawv. Kev tshawb nrhiav PHOOSPHOLIBID txuas ntxiv nthuav tawm cov sijhawm kev daws teeb meem kev noj qab haus huv thiab tsav tsheb tshiab hauv kev lag luam.
Tuaj txog::
Vance, De, & Kev Tawm Tsam, ND (1988). Lub methylation ntawm phosphatidylletylyletylethanine. Kev kawm hauv Lipid Tshawb Nrhiav, 27 (1), 61-79.
CUI, z., houweling, M., & Vance, de (1996). Kev qhia ntawm phosphatidyletylethanolamine n-methyltrans-2 hauv mitterrle-rh7777 Hepatoma Hlwb Kev Kho Mob Phosphatandylenymanoline thiab Triacyllglycerol pas. Phau ntawv Journal ntawm cov Ankmentistry, 271 (36), 21624-21631.
Hannun, ya, & obeid, lm (2012). Ntau lub ceramides. Phau ntawv Journal ntawm cov Ankmentistry, 287 (23), 19060-19068.
Kornhuam, J., medlin, A. Bleich, S., Jendrossek, V., Hiltfang, J., & Gulbins, E. (2005). Siab ua si ntawm cov kua qaub sphingomyelinase hauv kev nyuaj siab loj. Phau ntawv sau txog cov nqi sib kis noural, 112 (12), 1583-1590.
Krstic, D., & Knages, I. (2013). Decipherering tus mechanism nyob rau hauv lig-abset alzheimer tus kab mob. Xwm tshuaj xyuas kev cai neurology, 9 (1), 25-34.
Jiang, XC, Li, Z., & liu, R. (2018). Andreotti, g, revisiting qhov txuas ntawm phospholipids, o thiab atherosclerosis. Cov chaw kuaj mob lipidology, 13, 15-17.
Halliwell, B. (2007). Biochemistry ntawm oxidative kev nyuaj siab. Biochemical Society kev lag luam, 35 (5), 1147-1150.
Lattka, E., illig, T., Heinrich, J., & Koletzko, B. (2010). Puas yog cov roj ntsha hauv tib neeg lub mis tiv thaiv los ntawm kev rog? Cov ntaub ntawv thoob ntiaj teb kev rog, 34 (2), 157-163.
Cohn, JS, & Kamili, A. (2010). Wat, e, & Adeli, K, tawm cov luag hauj lwm ntawm proptilisin / kexin Hom 9 Inhibition metabolism thiab atherosclerosis. Cov Ntawv Qhia Atheroscleroscleroscleroscleroscleros tam sim no, 12 (4), 308-315 335.
Zeeple sh. Choline: Tseem ceeb lub luag haujlwm thaum me nyuam kev txhim kho thiab kev noj haus yuav tsum muaj nyob rau hauv cov neeg laus. Xyoo tau txais txiaj ntsig. 2006; 26: 229-50. DOI: 10.1146 / Annurev.nutr.26.061505.111156.
Liu l, Gang J, Srinivasarao M, li al. Phospholipid EICOSAPDID cov kua qaub-enriched acid-enriched phospholipids kom txhim kho neurobholipids nyob rau hauv cov nas nyob hauv qab no neonatal hypoxic-ischaemic hlwb raug mob. Pediatr res. 2020; 88 (1): 73-82. DOI: 10.18 / s41390-019-0637-8.
Garg R, Manghanda sc, Manchanda SC, Singla D. Lub luag haujlwm ntawm Cov Khoom Siv Tshuaj Tshiab Siv Cov Nanostars lossis Nanospheres. Qab teb af J bot. 2021; 139 (1): 109-120. DOI: 10.1016 / J.Sajb.2021.01.023.
Kelley, xws li, Albert, Ad, & Sullivan, MO (2018). Membrane lipids, eicosanoids, thiab lub synergy ntawm phospholmipid ntau haiv neeg, prostaglandins, thiab nitric oxide. Phau ntawv qhia kev sim ntawm kev sim tshuaj, 233, 235-270.
Van Mer, G., Voelker, Dr, Feigenson, GW (2008). Membrane lipids: qhov chaw uas lawv thiab lawv coj li cas. Xwm Xyuas Kev Ntsuam Xyuas Molecular Cell Biology, 9 (2), 112-124.
Benariba, N., Shambat, G., MSSAC, P., & cancSell, M. (2019). Kev nce qib ntawm kev lag luam synthesis ntawm phospholipids. Chemphyschem, 20 (14), 1776-1782.
Torchilin, VP (2005). Tsis ntev los no kev hloov kho nrog Liposomes ua cov kws nqa khoom siv. Pes Xwm Txheeb Xyuas Kev Tshawb Nrhiav Tshuaj Yeeb Tshuaj Siv, 4 (2), 145-160.
Brezesinski, G., Zhao, Y., & Gutberlet, T. (2021). Phospholipid kev sib tham: Topology ntawm lub taub hau, them nyiaj, thiab kev yoog tau. Tswv yim tam sim no nyob rau hauv colloid & interface science, 51, 81-93.
Abra, RM, & plob hav zoov, Ca (2019). Liposomal tshuaj kho cov tshuab: kev tshuaj xyuas nrog kev koom tes los ntawm biophysics. Tshuaj xyuas tshuaj xyuas, 119 (10), 6287-6306.
Allen, TM, & Cullis, PR (2013). Liposomal Cov Khoom Siv Yeeb Tshuaj Siv: Los ntawm cov tswvyim rau cov ntawv thov kho mob. Kev Tshuaj Ntsuam Siv Tshuaj Xyuas, 65 (1), 36-48.
Vance je, Vance de. Phospholipid biosynthesis hauv cov tsiaj cov tsiaj hauv cov tsiaj. Biochem xov tooj ntawm tes. 2004; 82 (1): 113-128. DOI: 10.1139 / O03-073
Van Mer G, Voelker Dr, Feigenson GW. Membrane lipids: qhov chaw uas lawv thiab lawv coj li cas. Nat Rev Mol Mol Mol BIOL. 2008; 9 (2): 112-124. DOI: 10.1038 / nrm2330
Boon J. Lub luag haujlwm ntawm phospholipids nyob rau hauv txoj haujlwm ntawm membrane protein. Biochim Biophys Acta. 2016; 1858 (10): 2256-2268. DOI: 10.1016 / J.BBAMEM.2016.02.030
Lub Sijhawm Post: Dec-21-2023
