Xov Xwm - Dab tsi lub ntuj antioxidant-ginkgo nplooj extract!

I. Kev qhia lus

Lub hauv paus rau phau ntawv

Cov txiaj ntsig kev noj qab haus huv ntawm Ginkgo Biloba Extract Plua (2)

Ginkgo nplooj ntoos extractyog cov khoom siv ntuj nquag muab extracted los ntawm ginkgo nplooj. Nws lub ntsiab lus tseemceeb yog flavonoids thiab ginkgo lactones. Nws yog cov paf tshwj xeeb (Platelel-activ, platelel-ua kom zoo) releptor thaiv kev thaiv. Nws cov kev ua si ntawm lub cev muaj xws li: txhim kho cerebral ncig thiab cell metabolism; Nce cov kev ua si ntawm cov qe ntshav liab superoxide dismutase (sod) thiab glutathione pev (glutathione peroxidase (gsh-px), thiab txo cell membrane potoxidized lipids (MDA). ntau lawm, scavenge dawb radicals, tiv thaiv kev puas tsuaj rau plawv rau Cardiomyocytes thiab vascular endothelial hlwb; Xaiv xaiv kev tiv thaiv plategent hartegation, micro thrombosis, thiab lipid metabolism tsis zoo los ntawm platelet paf; Txhim kho cov kev sib zog hauv lub siab thiab tiv thaiv Ischamic Myocardium; Nce qhov deformity ntawm cov qe ntshav liab, txo cov ntshav viscosity, thiab tshem tawm cov kab mob microcirculatory; inhibit cov synthesis ntawm thromboxane (TXIAT2) thiab txhawb txoj kev tso tawm ntawm Prostaglandin PGI2 los ntawm vascular endothelial hlwb.

Tsob Nroj Chaw

Ginkgo Biloba yog nplooj ntawm Ginkgo Biloba L., nroj tsuag ntawm tsev neeg Ginkgo. Nws extract (EGB) muaj ntau yam kev kho mob muaj ntau yam thiab yog siv dav hauv cov zaub mov thiab cov tshuaj pleev ib ce. Cov tshuaj lom neeg muaj kuab lom ntawm ginkgo nplooj yog qhov nyuaj heev, nrog ntau tshaj 140 Tebchaw raug rho tawm ntawm nws. Flavonoids thiab Terpene Lactones yog ob qho khoom xyaw tseem ceeb ntawm ginkgo nplooj. Tsis tas li ntawd, nws tseem muaj polyprenol, organic acids, polysaccharides, cov amino acids, thiab kab ntsiab lus. Raws li cov txheeb cais tsis tiav, cov nplooj ntawv thoob ntiaj teb tam sim no yog EGB761 tsim tawm rau lub teb chaws Yelemees Schwabe Schwabe Schwabe Schwabe Schwabe Schwabe Schwabe Schwabe schuas scheted txheej txheem. Nws zoo li xim av daj-daj hmoov thiab muaj ntxhiab tsw me ntsis ntawm ginkgo nplooj. Cov tshuaj lom neeg muaj kuab lom yog 24% flavonoids, 6% terpene lacicones, tsawg dua 0.0005% ginkoid, 7.0% tsis-flavonoid glycosides, thiab 4.0 polymer sib txuas. %, inorganic teeb 5.0%, noo kuab siv kuab tshuaj 3.0%, lwm tus 3.0%.

Antioxidant Cov yam ntxwv thiab kev sivchism

Ginkgo nplooj ntoos extract tuaj yeem tshem tawm cov Lipid dawb radicals, lipid peroxidation dawb radicals, thiab lwm yam. Nyob rau tib lub sijhawm, nws tseem tuaj yeem tswj hwm thiab txhim kho kev ua haujlwm ntawm antioxidant enzymes xws li superoxide dismutase thiab glutathione peroxidase. Cov nyhuv antioxidant ntawm flavonoids hauv egb tshaj li ntawm cov vitamins, thiab nws muaj los tiv thaiv radical cov khoom hauv vitro.

Cov teebmeem cuam tshuam antioxidant ntawm ginkgo rho tawm cov qauv sib txawv, thiab antioxidant cuam tshuam ntawm cov khoom siv crudacts thiab cov khoom ua kom zoo kuj sib txawv. Ma Xihan li al. pom tias puproleum ether-ethanol extract tau muaj zog tshaj tawm cov nyhuv antioxidant muaj cov roj rapeseed piv rau cov qauv kev npaj sib txawv tau los ntawm kev npaj sib txawv. Cov tshuaj antioxidant muaj peev xwm ntawm cov nplooj ginkgo nplooj ntoos tawm tau me ntsis siab dua li ntawm cov ua kom zoo. Qhov no tuaj yeem yog vim tias muaj kev rho tawm muaj lwm cov tshuaj tua kab mob antioxidant, cov amino acids, thiab lwm yam tshuaj uas muaj cov teebmeem synergistic.

Kev npaj txoj kev

(1) Organic Scolent extraction Street txoj kev tam sim no, feem ntau dav siv txoj hauv tsev thiab txawv teb chaws yog cov organic cov organic cov txheej txheem extraction. Txij li lwm cov kuab tshuaj organic yog tshuaj lom lossis tsis muaj zog, ethanol feem ntau yog siv los ua cov tshuaj tiv thaiv. Kev sim los ntawm Zhang yongong thiab lwm tus tau qhia tias qhov kev cuam tshuam zoo tshaj plaws yog 70%, tus naj npawb ntawm cov kev rho tawm yog 3 zaug, thiab txhua zaus refluxes rau 1.5 teev.

(2) enzyme extraction hom Wang Hui li al. Qhov kev xav tau ntau dua tom qab cov cellule tau pretreed, thiab cov txiaj ntsig tuaj yeem ncav cuag 2.01%.

(3) ultrasonic extraction txoj kev kho tom qab kev kho mob ultrasonic tau tawg, thiab kev txav mus los nrawm, uas txhawb nqa cov kev sib cais ntawm cov khoom xyaw nquag. Yog li no, ultrasonic extraction ntawm flavonoids muaj qhov zoo. Cov txiaj ntsig sim tau los ntawm liu jingzhi li al. Qhia tias cov txheej txheem ntawm cov txheej txheem ultrasonic extraction yog: Ultrasonic Tshaj Tawm Nyob rau lub sijhawm no, kev rho tawm tus nqi yog 81.9%.

Daim ntawv thov

Cov flavonoids nyob rau hauv ginkgo nplooj muaj antioxidant thaj chaw thiab tuaj yeem txuas ntxiv rau cov roj thiab pastries ua tshuaj tua kab mob antioxidants. Tag nrho cov flavonoids feem ntau daj thiab muaj dav dav-soluble thiab cov roj-soluble thiab tag nrho flavonoids tuaj yeem siv rau xim. Tus neeg sawv cev muaj txiaj ntsig. Ginkgo biloba yog ua tiav rau hauv ultrasfine hmoov thiab ntxiv rau cov khoom noj. Ginkgo nplooj yog ultra-finely pulverized thiab ntxiv rau ncuav, biscuits, khoom noj khoom haus, khoom noj khoom haus, thiab cov khoom noj rau hauv cov khoom noj ginkgo, thiab cov khoom noj khoom haus nrog cov khoom noj muaj mob nrog cov teebmeem.
Ginkgo nplooj ntawv rho tawm yog siv los ua khoom noj ntxiv hauv Canada thiab tau pom zoo los ntawm cov tshuaj uas dhau los ntawm lub teb chaws Yelemees thiab Fabkis. Ginkgo nplooj muaj nyob hauv Tebchaws Meskas Cov Chaw muag khoom (24 tsab cai) thiab tuaj yeem siv ua kev noj haus ntxiv hauv Tebchaws Meskas.

Pharmacological cuam tshuam

1. Cov nyhuv ntawm cov hlab plawv
(1) nplooj nplooj tawm tuaj yeem inhibit qhov kev ua si ntawm angiodensin-hloov cov hlab ntsha (Ace) nyob rau hauv tib neeg lub cev, ua rau cov ntshav tawm tsam, thiab ua kom ntshav ntws.
(2) nplooj nplooj tawm tuaj yeem tiv thaiv kev ua haujlwm ntawm cov txiv neej thiab npua los ntawm kev ua haujlwm ntawm hypolacaine, thiab ua kom muaj kev tiv thaiv kev ua txhaum cai) ua rau muaj kev sib deev) ua rau muaj cov dev arhythmia. Nws tuaj yeem txwv tsis pub muaj kev ua tiav.
(3) nplooj nplooj tawm tuaj yeem nthuav dav cov hlab ntshav ntawm cov ntshav pleev thiab cov dev, nce cerebral ntshav, thiab txo qis nqi kev kubascular tsis kam. Ginkgo nplooj ntoos tawm tuaj yeem tiv thaiv qhov nce hauv mesentry microvascular txoj kab uas hla los ntawm enavenous endotoxin. Nyob rau hauv canine endotoxin qauv, ginkgo biloba extract inhit inhtodynamic hloov; Nyob rau hauv cov yaj mob ntsws qauv, ginkgo biloba extract inhibits bypertension thiab pulmonary edeme tshwm sim los ntawm lymphatic ntws disorder tshwm sim los ntawm endotoxin.
(4) cov nas tsuag tau intraperitoneally txhaj nrog 5ml / kg ntawm ginkgo nplooj flavonids txhua hnub. Tom qab 40 hnub, cov ntshav ntshiab cov ntsiab lus tau txo qis. Ginkgo Biloba extract (20 mg / kg ib hnub) tau muab cov lus qhia txog luav tau txais ib txwm muaj thiab hypercholemic noj. Tom qab ib hlis twg, cov qib hyper-esterified choleslivol nyob rau ntshav thiab aorta ntawm cov luav tau txais cov zaub mov muaj tshuaj tiv thaiv tau txo qis. Txawm li cas los xij cov roj (cholesterol) tsis hloov pauv.
(5) Txuas ntxiv terpene lactone yog cov PAF tshwj xeeb tau txais kev pab ntsa iab. Ginkgo nplooj ntoos tawm lossis ginkgo terpene lactone tuaj yeem inibit Platelet Platelet-ua kom zoo (PAF) thiab cyclooxygenase lossis lipoxyenased. Ginkgo nplooj ntawv rho tawm tau zoo zam thiab thaiv kev ua pa tawm los ntawm PAF tab sis tsis muaj kev cuam tshuam kev sib sau los ntawm ADP.

2. Cov nyhuv rau hauv nruab nrab ntawm cov leeg hlwb
(1) nplooj nplooj txaus cuam tshuam rau cov txheej txheem endocrine thiab kev sib cuam tshuam ntawm lub cev tiv thaiv kab mob thiab lub plawv nruab nrab los ntawm kev ua ntawm PAF. Nws tuaj yeem txhawb kev ncig lub hlwb thiab txhim kho kev nco lub luag haujlwm.
(2) Ginkgo Terpene Lactones muaj cov tshuaj tiv thaiv kev tawm tswv yim, thiab lawv cov tshuaj tiv thaiv kev ntxhov siab cuam tshuam nrog lub plawv nruab nrab monesininity hlab ntsha.
(3) Ntxiv rau qhov tseeb tias nplooj nplooj ntawv ginkgo tuaj yeem txhim kho qhov tsis txaus siab rau nws cov ntshav hauv lub hlwb thiab kev txhim kho ntawm lub hlwb metabolism hauv lub sijhawm hypoxia.
(4) nplooj nplooj ginkgo zoo heev txhim kho lub hlwb kev coj tsis zoo ntawm gerbilculation ntawm gerbils hauv gerbils los ntawm ischemia thiab congestion; Txhim kho txoj haujlwm ntawm cov dev tom qab ntau-focal lub hlwb ischemia rov qab los ntawm neuronal kev puas tsuaj tom qab ischemia hauv lub hlwb gerbil; Zoo heev txo qhov poob ntawm ATP, amp, creatine thiab creation phosphate hauv ischemic lub hlwb ntawm tus poj niam huab. Ginkgo Biloba Lactone B muaj txiaj ntsig hauv kev kho mob kho mob mob stroke.

3. Cov nyhuv ntawm lub plab zom mov
(1) Ginkgo nplooj ntawv rho tawm tuaj yeem txhim kho cov plab hnyuv thiab plab hnyuv rwj hauv nas los ntawm PAF thiab endotoxin, thiab tuaj yeem ua rau muaj kev puas tsuaj hauv plab zom mov.
(2) Hauv nas nrog rau lub siab ualrhosis los ntawm kev ua kom cov ntshav siab, thiab cov ntshav ntws los ntawm cov kab hiav txwv sib dhos, thiab txhim kho kev tiv thaiv kev kub ntxhov ntau ntxiv piv nrog cov placebo. Qhov no qhia tau hais tias nplooj nplooj ginkgo muaj kev kho mob muaj peev xwm rau daim siab ua kom mob siab. Nws tuaj yeem thaiv qhov tsim ntawm cov pa oxygen-radicals hauv cov nas phem heev los ntawm Chocecystokinin. Ginkgo Terpene Lactone B Tej zaum yuav muaj lub luag haujlwm ntawm kev kho mob ntawm pancreatitis.

4. Nyuaj rau lub tshuab ua pa
(1) Cov ethanol extract ntawm ginkgo biloba muaj cov txiaj ntsig ncaj qha rau cov leeg nqaij daim tawv thiab tshuaj pleev hawb pob, thiab tiv thaiv tus mob hawb pob tawm tsam hauv Guinea npua.
(2) Kev txhaj tshuaj nplooj ntawm ginkgo nplooj extract tuaj yeem inhibit lub bronchoconstriction thiab hilperbuminity ntawm ovgrens, tab sis tsis cuam tshuam rau lub bronchial hyperrescon.
(3) Kev nqus tau ntawm aerosolized ginkgo nplooj extract tsis yog txwv tsis pub muaj ntshav dawb thiab eosinophils tshwm sim los ntawm PAF. Ginkgo nplooj ntawv Extract yog qhov tseem ceeb tseem ceeb nyob rau hauv inhibiting thiab kho cov kaus mom tawv ncauj.

5. Los tiv thaiv kev laus
Ginkobiflavonoids, Isoginkgobiflavonoids, ginkgo biloba, thiab querco nplooj tag nrho cov ntxaij peribidation, tshwj xeeb tshaj yog txij li cov tsiaj loj muaj zog inhibitory. Cov kev sim tau ua rau cov nas thiab nws tau pom tias cov nplooj ntoo uas muaj tag nrho flavonids tag nrho cov flavonoids tag nrho cov flavonids tag nrho

7. Lub luag haujlwm hauv kev hloov kev tsis lees paub thiab lwm yam kev tawm tsam
Ginkgo nplooj ntawv Extract tuaj yeem ua kom lub sijhawm muaj sia nyob ntev ntawm daim tawv nqaij grafts, herototopic plawv xenografts, thiab ortotopic lub siab xenografts. Ginkgo nplooj ntoos tawm tuaj yeem inhibit lub cev minerter cell ua si tiv thaiv kab mob KC526, thiab tseem tuaj yeem tiv thaiv lub ntuj tua neeg ua rau los ntawm Interferon.

8. Cov nyhuam tawm tsam
Cov crude extract ntawm nplooj ntsuab ntawm ginkgo biloba, cov rog-soluble feem, tuaj yeem inhibit tus kab mob Epstein-Barr. Heptadecene salicylic acid thiab bilo-betin muaj cov kev ua haujlwm ruaj khov; Tag nrho cov flavonoids ntawm ginkgo tuaj yeem nce qhov thymus qhov hnyav ntawm cov qog-bearing nas. thiab cov qib kev ua si, ua kom lub cev tiv thaiv kev tiv thaiv qog nqaij hlav; QrealdeTin thiab myricetin tuaj yeem inhibit qhov tshwm sim ntawm carcinogens.

Cov ntawv sau thiab cov contraindications

Cov kev sib raug zoo ntawm ginkgo nplooj extract: qee zaus cov plab zom mov tsis xis nyob, xws li anorexia, xeev siab, quav quav, mob plab, thiab lwm yam; Kuj tseem yuav tau nce lub plawv, qaug zog, thiab lwm yam, tab sis cov no tsis cuam tshuam rau kev kho. Tom qab kev tswj hwm lub qhov ncauj ntev ntev, cuam tshuam ntawm cov ntsuas ntshav yuav tsum tau txais kev saib xyuas ntshav kom tsis tu ncua. Yog tias koj muaj cov tsos mob plab zom mov, koj tuaj yeem nqa nws tom qab noj mov xwb.

Kev sib cuam tshuam yeeb tshuaj

Cov khoom no muaj cov nyhuv symistic thaum siv ua ke nrog lwm cov ntshav viscosity-cov khoom siv cov ntshav, xws li lwm yam tuaj yeem txhim kho kev ua tau zoo.

Kev Loj Hlob Qauv

Ginkgo nplooj muaj me me ntawm proantocyanidins thiab urushiolic acids, uas tseem muaj kuab paug rau tib neeg lub cev. Thaum ginkgo nplooj ua cov khoom raw ua cov khoom noj, kev kho mob tshwj xeeb yog yuav tsum tau txo cov ntsiab lus ntawm Proantocyanidins thiab Urushiolic acids. Txawm li cas los xij, nyob rau hauv cov kev siv tshuaj tam sim no, tsis muaj mob lossis muaj mob hnyav thiab tsis muaj qhov mob Teratogenic. Ministry of Health Goessed Ginkgo Biloba extract ua cov zaub mov tshiab ntxiv nyob rau xyoo 1992. Nyob rau hauv kev lag luam khoom noj khoom haus tshiab hauv xyoo 1992. Nyob rau hauv kev lag luam khoom noj khoom haus, thiab kev tshawb fawb thiab kev txhim kho ntawm cov khoom lag luam.