Sinomenine Hydrochloride Hmoov
Sinomenine Hydrochloride yog cov tshuaj sib xyaw ua ke los ntawm cov nroj tsuag Sinomenium acutum, uas feem ntau pom nyob rau sab hnub tuaj Asia. Nws yog ib qho alkaloid uas tau siv ib txwm siv hauv Suav tshuaj rau nws cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob. Daim ntawv hydrochloride yog cov ntsev uas txhim kho qhov sib xyaw ua ke thiab kev ruaj ntseg, ua rau nws tsim nyog rau kev siv tshuaj.
Sinomenine Hydrochloride tau kawm txog nws cov txiaj ntsig kev kho mob hauv kev kho mob xws li mob caj dab rheumatoid, vim nws muaj peev xwm hloov kho lub cev tiv thaiv kab mob thiab txo qhov mob. Nws ua hauj lwm los ntawm inhibiting zus tau tej cov pro-inflammatory cytokines thiab lwm yam neeg nruab nrab koom nyob rau hauv lub inflammatory teb.
Ntxiv nrog rau nws cov tshuaj tiv thaiv kab mob thiab tshuaj tua kab mob, Sinomenine Hydrochloride kuj tau pom muaj peev xwm hauv neuroprotection, anti-fibrosis, thiab kev tiv thaiv qog nqaij hlav hauv ntau yam kev tshawb fawb preclinical.
Lub Npe: (9a,13a,14a)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-one, monohydrochloride
CAS Nr .: 6080-33-7
Synonyms: Cucoline NSC 76021
Molecular Formula: C19H23NO4 • HCl
Cov roj formula: 365.9
Purity: ≥98% Ib qho crystalline khoom
Solubility (Kawm txog Variance hauv Solubility)
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 5 mg/ml
PBS (pH 7.2): 5 mg/ml
Keeb kwm: Cog/Sinomenium acutum
Shipping & Storage Information:
Cia - 20 ° C
Shipping: Chav ntsuas kub
Kev ruaj ntseg: ≥ 4 xyoos
| Yam khoom | Specification | Kev tshwm sim |
| Kev ntsuam xyuas (HPLC) | 98.0% | 98.12% |
| Qhov tshwm sim | hmoov dawb | Ua raws |
| Particle Loj | 98% txog 80 mesh | Ua raws |
| tsw | Yam ntxwv | Ua raws |
| Saj | Yam ntxwv | Ua raws |
| Cov yam ntxwv ntawm lub cev | ||
| Poob rau ziab | ≤ 0.5% | 0.38% |
| Tshauv | ≤ 0.5% | 0.46% |
| Cov hlau hnyav | ||
| Cov hlau hnyav (raws li Pb) | USP cov qauv (<10ppm) | <10ppm |
| Arsenic (As) | ≤ 2ppm | 0.78 ppm ua |
| Lead (Pb) | ≤ 2ppm | 1, 13 ppm |
| Cadmium (Cd) | ≤ lppm | 0, 36 ppm |
| Mercary (Hg) | ≤ 0.1ppm | 0, 01 ppm |
| Tshuaj tua kab | Tsis kuaj pom | Tsis kuaj pom |
| Total PlateCount | NMT 10000cfu/g | 680 cf / g |
| Total Poov & Pwm | NMT 100cfu/g | 87 cf/g ib |
| E. Coli | NMT 30cfu/g | 10 cfu/g |
| Salmonella | Tsis zoo | Tsis zoo |
| Xaus | Ua raws li Enterprise Standard | |
Cov teebmeem tseem ceeb ntawm Sinomenine Hydrochloride muaj xws li:
(1) Anti-inflammatory: txo qhov mob.
(2) Analgesic: muab qhov mob nyem.
(3) Immunosuppressive: Txhawb kev tiv thaiv kab mob.
(4) Anti-rheumatic: kho mob rheumatoid mob caj dab.
(5) Neuroprotective: Tiv thaiv cov paj hlwb los ntawm kev puas tsuaj.
(6) Anti-fibrotic: Tiv thaiv lossis txo cov nqaij mos fibrosis.
Sinomenine Hydrochloride feem ntau yog siv rau hauv cov hauv qab no:
(1) Rheumatology: Kev kho mob rheumatoid mob caj dab.
(2) Kev Tswj Kev Mob: Kev txo qis ntawm qhov mob ntev.
(3) Anti-inflammatory: txo qhov mob.
(4) Immunomodulation: Modulation ntawm lub cev tiv thaiv kab mob.
(5) Neuroprotection: Muaj peev xwm siv tau hauv kev kho mob neuroprotective.
Cov txheej txheem tsim khoom ntawm Sinomenine Hydrochloride Powder tuaj yeem ua tiav raws li hauv qab no:
Kev npaj tshuaj ntsuab:Ntxuav thiab ziab cov khoom nyoos cog.
Extraction:Siv cov kuab tshuaj xws li ethanol los rho tawm sinomenine los ntawm cov khoom cog.
Concentration:Evaporating cov kuab tshuaj kom mloog zoo rau cov ntsiab lus sinomenine.
Alkalization:Kho cov pH los hloov sinomenine rau nws daim ntawv ntsev.
Kua-kua Extraction:Purifying nrog cov kuab tshuaj organic xws li anisol lossis 1-heptanol.
Ntxuav:Aqueous ntxuav kom tshem tawm impurities thiab hnyav kab.
Acidification:Txo cov pH kom precipitate sinomenine hydrochloride.
Crystallization:Tsim cov crystals ntawm sinomenine hydrochloride.
Kev sib cais:Centrifuging los yog lim kom cais cov muaju los ntawm cov tshuaj.
Kev ziab:Tshem tawm cov dej seem ntawm cov muaju.
Milling:Sib tsoo cov pob zeb qhuav rau hauv cov hmoov zoo.
Sieving:Ua kom muaj kev sib faib particle loj faib.
Kev Tswj Xyuas Zoo:Kev ntsuas purity, concentration, thiab microbiological qauv.
Ntim:Sterile thiab ruaj ntseg ntim rau kev faib khoom.
Cia: Khaws nyob rau hauv qhov chaw txias, qhuav, thiab huv si, tiv thaiv los ntawm noo noo thiab ncaj qha teeb.
Ntim Pob: 25kg / nruas.
Lub Sijhawm Lead: 7 hnub tom qab koj xaj.
Lub neej txee: 2 xyoos.
Lus Cim: Customized specifications kuj tuaj yeem ua tiav.
Qhia
Hauv 100kg, 3-5 Hnub
Qhov rooj rau qhov rooj kev pabcuam yooj yim tuaj tos cov khoom
Los ntawm Hiav Txwv
Tshaj 300kg, Nyob ib ncig ntawm 30 Hnub
Chaw nres nkoj rau chaw nres nkoj kev pab cuam clearance broker xav tau
Los ntawm Cua
100kg-1000kg, 5-7days
Tshav dav hlau mus rau tshav dav hlau kev pab cuam clearance broker xav tau
Bioway Organic tau txais USDA thiab EU organic, BRC, ISO, HALAL, KOSHER, thiab HACCP daim ntawv pov thawj.
