Sinomenine hydrochloride hmoov

Anti-mob: txo qhov o.
Analgesic: muab tshuaj kom mob.
Immunosuppressive: suppresses tiv thaiv kab mob.
Anti-rheumatic: kho mob mob rheumatoid mob caj dab.
Neuroprotrective: Tiv thaiv cov hlab ntsha hlwb los ntawm kev puas tsuaj.
Anti-fibrotic: tiv thaiv lossis txo cov ntaub so ntswg ntawm fibrosis.

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Khoom Qhia Qhia

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Khoom Taw Qhia

Hmoov tsis zoo yog cov tshuaj sib xyaw ua ke los ntawm cov nroj tsuag sinomenium acutum, uas feem ntau pom nyob rau sab hnub tuaj Asia. Nws yog cov alkaloid uas tau siv nyob rau hauv Suav cov tshuaj rau nws cov tshuaj tiv thaiv thiab cov khoom analgesic. Lub fydrochloride daim ntawv yog ntsev uas txhim kho cov sib xyaw ua solubility thiab ruaj khov, ua rau nws tsim nyog rau kev siv tshuaj.
Hmoov tsis hydrochloride tau kawm rau nws cov peev xwm kho tau mob xws li kev mob caj dab xws li nws lub peev xwm los hloov kev tiv thaiv kab mob ntawm lub cev thiab cov tshuaj o. Nws ua haujlwm los ntawm inhibiting kev tsim cov pro-inflammatory cytokines thiab lwm cov neeg sib pab nrog cov neeg tua hluav taws.
Ntxiv nrog rau nws cov kev cuam tshuam thiab kev ua kom muaj txiaj ntsig, sinomenine hydrochloride kuj tseem muaj peev xwm ua rau muaj kev ntxhov siab, tshuaj tiv thaiv cov tub ntxhais kawm hauv ntau qhov kev tshawb fawb.

Kev qhia tshwj xeeb

Lub npe: (9A, 13a, 14a) -7,8-didehydro-3,7-Didehyoxy-11-ib, ib, monohydrochloride
Tus Naj Npawb: 6080-33-7
Txhais lus: Cucoline NSC 76021
Molecular cov mis: c19h23no4 • hcl
Mis Light: 365.9
Purity: ≥98% ib cov khoom siv crystalline
Solubility (kawm txog kev sib txawv hauv solubility)
DMF: 30 mg / ml
DMOs: 30 mg / ml
Ethang: 5 mg / ml
PBS (PH 7.2): 5 mg / ml
Keeb kwm: Nroj / Sinomenium Acrum
Cov ntaub ntawv thauj khoom & khoom cia:
Cia -20 ° C
Shipping: Chav Chav
Ruaj khov: ≥ 4 xyoos

Yam	Kev qhia tshwj xeeb	Qho kawg
Assisy (hplc)	98.0%	98.12%
Kev tshwm sim	Cov hmoov dawb	Ua raws
Qhov loj me me	98% los ntawm 80mesh	Ua raws
Tus ntxhiab	Tus yam ntxwv	Ua raws
Saj	Tus yam ntxwv	Ua raws
Cov yam ntxwv ntawm lub cev
Poob rau ziab	I≤0.5%	0.38%
Txhos	I≤0.5%	0.46%
Cov hlau hnyav
Cov hlau hnyav (raws li pb)	USP Cov Qauv (<10ppm)	<10ppm
Arsenic (raws li)	IOS no	0.78ppm
Txhuas (PB)	IOS no	1.13pplm
Cadmium (CD)	15TENLPPM	0.36ppm
Mercary (Hg)	I≤0.1PPM	0.01ppm
Cov Khoom Noj Tshuaj Ntaus Cia	Tsis yog kuaj xyuas	Tsis yog kuaj xyuas
Tas Nrho Qav	Nmt 10000cfu / g	680 cfu / g
Tag nrho cov poov xab & pwm	Nmt 100cfu / g	87 cfu / g
E.coli	Nmt 30cfu / g	10 cfu / g
Tus ntses siav	Tsis zoo	Tsis zoo
Tag	Conforms rau cov qauv enterprise

Nta

Lub ntsiab cuam tshuam ntawm sinomenine hydrochloride muaj xws li:
(1) Tiv Thaiv Cov Mob: Txo cov mob o.
(2) analgesic: muab qhov mob nyem.
(3) immunosuppressive: suppresses cev ua haujlwm.
(4) Los tiv thaiv rheumatic: kho mob rheumatoid mob caj dab.
(5) Neuropprotective: tiv thaiv cov hlab hlwb los ntawm kev puas tsuaj.
(6) tiv thaiv kev nplua: tiv thaiv lossis txo cov ntaub so ntswg.

Daim ntawv thov

Sinomenine hydrochloride feem ntau yog siv nyob rau hauv cov chaw hauv qab no:
(1) Rheumatology: kev kho mob rheumatoid mob caj dab.
(2) Kev tswj hwm qhov mob: kev nyuaj siab ntawm kev mob mob ntev.
(3) Los tiv thaiv mob: txo cov tshuaj o.
(4) immunomodulation: kev tawm tsam ntawm lub cev tiv thaiv kab mob.
(5) kev neuroprotection: Muaj peev xwm siv hauv kev kho mob neuroprotrotive.

Cov ntsiab lus ntau lawm

Cov txheej txheem ntau lawm ntawm Sinomenine hydrochloride tej hmoov yuav yog teev tau raws li hauv qab no:

Kev npaj tshuaj ntsuab:Kev ntxuav thiab kom qhuav cov khoom siv cov khoom siv.
Extraction:Siv cov kuab tshuaj zoo li ethanol kom rho tawm syomenerine los ntawm cov khoom ntoo.
Concentration:Evaporating cov kuab tshuaj kom mloog cov ntsiab lus sinomenine.
Alkalization:Kho cov ph thiaj li hloov ua ke mus rau nws cov ntsev.
Kua ua kua extraction:Kev ua kom dawb huv nrog cov kuab tshuaj organic zoo li anisole lossis 1-heptanol.
Ntxuav:Aqueous ntxuav kom tshem tawm impurities thiab kuab tshuaj kab ke.
Acidification:Txo cov ph tuaj txog rau daus daus Dinomenine hydrochloride.
Crystallization:Ua kev muaju ntawm sinomenine hydrochloride.
Sib cais:Centrifuging los yog lim kom cais cov muaju los ntawm kev daws teeb meem.
Drying:Tshem tawm cov kev ua haujlwm nyob ntawm lub muaju.
Milling:Sib tsoo cov qhuav muaju rau hauv cov hmoov zoo.
Sieving:Txhim kho cov khaub ncaws uniform qhov loj me me faib.
Tswjhwm Zoo:Kev tshuaj ntsuam xyuas kev coj dawb huv, concentration, thiab cov qauv microbiological.
Ntim:Ntim tsis muaj menyuam thiab muaj kev nyab xeeb rau kev faib tawm.

Ntim thiab cov kev pabcuam

Cia: Cia rau hauv qhov chaw txias, qhuav, thiab huv si, tiv thaiv los ntawm ya raws thiab lub teeb ncaj qha.
Bulk pob: 25kg / nruas.
Lub Sijhawm Lead: 7 hnub tom qab koj xaj.
Txee lub neej: 2 xyoos.
Cim: Cov lus qhia tshwj xeeb kuj tuaj yeem ua tiav.