Pure Methyltetrahydrofolate Calcium (5MTHF-Ca)
Pure Methyltetrahydrofolate Calcium (5-MTHF-Ca) yog ib hom folate uas muaj bioavailable heev thiab tuaj yeem siv tau yooj yim los ntawm lub cev. Nws yog calcium ntsev ntawm methyltetrahydrofolate, uas yog lub luag haujlwm ntawm folate hauv lub cev. Folate yog ib qho tseem ceeb ntawm cov vitamin B uas ua lub luag haujlwm tseem ceeb hauv ntau cov txheej txheem ntawm tes, suav nrog DNA synthesis, kev tsim cov qe ntshav liab, thiab lub paj hlwb ua haujlwm.
MTHF-Ca feem ntau yog siv los ua kev noj haus ntxiv los txhawb cov qib folate hauv cov tib neeg uas yuav muaj teeb meem metabolizing lossis nqus cov khoom hluavtaws ntawm folic acid pom hauv cov khoom noj muaj zog thiab cov tshuaj ntxiv. Nws muaj txiaj ntsig tshwj xeeb rau cov tib neeg uas muaj qee yam kev hloov pauv caj ces uas tuaj yeem cuam tshuam cov metabolism hauv folate.
Ntxiv nrog rau MTHF-Ca tuaj yeem pab txhawb kev noj qab haus huv thiab kev noj qab haus huv tag nrho, tshwj xeeb tshaj yog nyob rau hauv thaj chaw xws li kev noj qab haus huv ntawm lub plawv, kev loj hlob ntawm neural tube thaum cev xeeb tub, kev paub txog kev ua haujlwm, thiab kev tswj kom zoo. Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias MTHF-Ca yuav tsum tau siv raws li kev qhia ntawm tus kws kho mob, tshwj xeeb tshaj yog rau cov tib neeg uas muaj mob tshwj xeeb lossis cov uas noj qee yam tshuaj.
| Khoom npe: | L-5-Methyltetrahydrofolate calcium |
| Synonyms: | 6S-5-Methyltetrahydrofolate calcium; Calcium L-5-Methyltetrahydrofolate; Levomefolate calcium |
| Molecular Formula: | C20H23CaN7O6 |
| Molecular Luj: | 497.52 ib |
| CAS Nr: | 151533-22-1 |
| Cov ntsiab lus: | ≥ 95.00% los ntawm HPLC |
| Qhov tsos: | Dawb mus rau lub teeb daj crystalline hmoov |
| Lub teb chaws ntawm keeb kwm: | Tuam Tshoj |
| Pob: | 20kg / nruas |
| Lub neej txee: | 24 hli |
| Cia: | Khaws rau hauv qhov chaw txias & qhuav. |
| Cov khoom | Specifications | Cov txiaj ntsig |
| Qhov tshwm sim | Dawb los yog dawb hmoov hmoov | Paub meej |
| Kev txheeb xyuas | Qhov zoo | Paub meej |
| Calcium | 7.0% -8.5% | 8.4% |
| D-5-Methylfolate | ≤1.0 | Tsis pom |
| Residue ntawm ignition | ≤ 0.5% | 0.01% |
| Dej | ≤ 17.0% | 13.5% |
| Kev ntsuam xyuas (HPLC) | 95.0% -102.0% | 99.5% |
| Tshauv | ≤0.1% | 0.05% |
| Hnyav Hlau | ≤ 20 ppm | Paub meej |
| Tag Nrho Phaj suav | ≤1000cfu / g | Tsim nyog |
| Yeast & Pwm | ≤100cfu / g | Tsim nyog |
| E.coil | Tsis zoo | Tsis zoo |
| Salmonella | Tsis zoo | Tsis zoo |
High bioavailability:MTHF-Ca yog ib hom folate uas muaj bioavailable heev, txhais tau tias nws tuaj yeem nqus tau yooj yim thiab siv los ntawm lub cev. Qhov no yog qhov tseem ceeb vim tias qee tus neeg yuav muaj teeb meem hloov cov hluavtaws folic acid rau hauv nws daim ntawv nquag.
Active daim ntawv folate:MTHF-Ca yog hom folate, hu ua methyltetrahydrofolate. Daim ntawv no tau yooj yim siv los ntawm lub cev thiab tsis tas yuav muaj cov txheej txheem hloov dua siab tshiab ntxiv.
Calcium ntsev:MTHF-Ca yog calcium ntsev, uas txhais tau hais tias nws yog khi rau calcium. Qhov no muab cov txiaj ntsig ntxiv ntawm calcium ntxiv nrog rau kev txhawb nqa folate. Calcium yog qhov tseem ceeb rau cov pob txha noj qab haus huv, cov leeg ua haujlwm, cov paj hlwb, thiab lwm yam haujlwm ntawm lub cev.
Haum rau cov tib neeg uas muaj kev hloov pauv caj ces tshwj xeeb:MTHF-Ca muaj txiaj ntsig tshwj xeeb rau cov tib neeg uas muaj qee yam kev hloov pauv caj ces uas tuaj yeem cuam tshuam cov metabolism hauv folate. Cov kev hloov caj ces no tuaj yeem cuam tshuam rau lub cev lub peev xwm los hloov folic acid rau hauv nws daim ntawv nquag, ua ntxiv nrog cov folate tsim nyog.
Txhawb ntau yam ntawm kev noj qab haus huv:MTHF-Ca supplementation tuaj yeem pab txhawb kev noj qab haus huv thiab kev noj qab haus huv tag nrho. Nws muaj txiaj ntsig tshwj xeeb rau kev noj qab haus huv ntawm cov hlab plawv, kev loj hlob ntawm neural tube thaum cev xeeb tub, kev paub txog kev ua haujlwm, thiab kev tswj kom zoo.
Pure Methyltetrahydrofolate Calcium (MTHF-Ca) muaj ntau yam txiaj ntsig kev noj qab haus huv:
Folate metabolism txhawb:MTHF-Ca yog ib qho bioavailable heev thiab nquag folate. Nws pab txhawb lub cev folate metabolism, uas yog ib qho tseem ceeb rau DNA synthesis, cov ntshav liab tsim, thiab tag nrho cov cellular muaj nuj nqi.
Cardiovascular Health:Cov qib folate txaus yog qhov tseem ceeb rau kev noj qab haus huv ntawm cov hlab plawv. MTHF-Ca supplementation tuaj yeem pab txo qis homocysteine , cov amino acid uas, thaum nce siab, cuam tshuam nrog kev pheej hmoo ntawm cov kab mob plawv.
Kev txhawb nqa cev xeeb tub:MTHF-Ca yog ib qho tseem ceeb thaum cev xeeb tub, vim nws pab tiv thaiv cov hlab ntsha neural hauv kev loj hlob fetuses. Nws raug pom zoo rau cov poj niam uas muaj hnub nyoog yug me nyuam kom ntseeg tau tias lawv muaj cov qib folate txaus, tshwj xeeb tshaj yog thaum ntxov ntawm cev xeeb tub.
Kev tswj kev xav:Folate plays lub luag haujlwm tseem ceeb hauv neurotransmitter synthesis. Cov qib folate txaus txhawb kev tsim cov serotonin, dopamine, thiab norepinephrine, uas yog ib qho tseem ceeb rau kev tswj kom zoo. MTHF-Ca supplementation yuav muaj txiaj ntsig zoo rau cov tib neeg uas muaj kev xav tsis zoo, xws li kev nyuaj siab.
Kev paub txog kev ua haujlwm:Folate yog qhov tseem ceeb rau kev paub txog kev ua haujlwm thiab lub hlwb noj qab haus huv. MTHF-Ca supplementation tuaj yeem pab txhawb kev nco, kev xav, thiab kev paub txog tag nrho, tshwj xeeb tshaj yog cov laus.
Kev txhawb nqa zaub mov:MTHF-Ca supplementation tuaj yeem muaj txiaj ntsig zoo rau cov tib neeg uas muaj kev hloov pauv caj ces uas cuam tshuam rau cov metabolism hauv folate. Cov tib neeg no yuav muaj teeb meem hloov cov hluavtaws folic acid rau hauv nws daim ntawv nquag. MTHF-Ca muab daim ntawv nquag ntawm folate ncaj qha, hla txhua qhov teeb meem hloov pauv.
Nutraceuticals thiab kev noj zaub mov ntxiv:MTHF-Ca feem ntau yog siv los ua cov khoom tseem ceeb hauv cov khoom noj khoom haus thiab nutraceuticals. Nws muab cov folate uas muaj bioavailable heev, muab ntau yam txiaj ntsig kev noj qab haus huv, raws li tau hais dhau los.
Khoom noj khoom haus thiab dej haus fortification:MTHF-Ca tuaj yeem muab tso rau hauv cov khoom noj thiab dej haus los txhawb lawv nrog folate. Qhov no yog qhov tseem ceeb tshwj xeeb tshaj yog rau cov khoom lag luam uas ua rau cov neeg muaj folate tsis txaus lossis xav tau folate ntau ntxiv, xws li cov poj niam cev xeeb tub lossis cov neeg muaj qee yam mob.
Pharmaceutical formulations:MTHF-Ca tuaj yeem siv rau hauv cov tshuaj formulations raws li cov khoom xyaw nquag. Nws tuaj yeem siv rau hauv cov tshuaj tsom rau cov xwm txheej tshwj xeeb ntsig txog folate deficiency lossis folate metabolism tsis zoo, xws li ntshav ntshav lossis qee yam kab mob caj ces.
Kev saib xyuas tus kheej thiab tshuaj pleev ib ce:MTHF-Ca qee zaum suav nrog cov khoom tu tus kheej thiab tshuaj pleev ib ce vim nws cov txiaj ntsig zoo rau kev noj qab haus huv ntawm daim tawv nqaij. Folate koom nrog ntau yam txheej txheem ntawm tes ntawm daim tawv nqaij thiab tuaj yeem ua rau nws tag nrho kev noj qab haus huv thiab zoo li.
Tsiaj pub:MTHF-Ca kuj tuaj yeem muab tso rau hauv cov tsiaj pub ntxiv rau tsiaj nrog folate. Qhov no yog tshwj xeeb tshaj yog muaj feem xyuam rau cov tsiaj txhu thiab nqaij qaib industries, qhov twg kom muaj kev noj haus txaus rau kev loj hlob thiab kev noj qab haus huv yog qhov tseem ceeb.
Cov ntawv thov no qhia txog ntau yam ntawm MTHF-Ca thiab nws cov peev xwm siv tau hauv ntau qhov kev lag luam los daws cov kev txhawj xeeb txog kev noj qab haus huv folate thiab kev xav tau kev noj haus. Txawm li cas los xij, nws yog ib qho tseem ceeb uas yuav tsum ua raws li cov lus qhia noj kom raug thiab sab laj nrog cov kws tshaj lij thaum koom nrog MTHF-Ca rau hauv ib qho khoom lossis kev tsim.
Kev tsim cov khoom siv raw:Cov txheej txheem pib nrog cov khoom siv raw khoom zoo. Cov khoom siv tseem ceeb uas xav tau rau kev tsim MTHF-Ca yog folic acid thiab calcium ntsev.
Kev hloov pauv ntawm folic acid rau 5,10-Methylenetetrahydrofolate (5,10-MTHF):Folic acid hloov mus rau 5,10-MTHF los ntawm kev txo qis. Cov kauj ruam no feem ntau suav nrog kev siv cov tshuaj txo qis xws li sodium borohydride lossis lwm yam khoom siv uas tsim nyog.
Convert 5.10-MTHF to TZSLub 5,10-MTHF yog ntxiv rau cov tshuaj calcium uas tsim nyog, xws li calcium hydroxide lossis calcium carbonate, los ua Methyltetrahydrofolate Calcium (MTHF-Ca). Cov txheej txheem no suav nrog kev sib xyaw cov reactants thiab tso cai rau lawv los ua raws li kev tswj hwm, suav nrog qhov kub thiab txias, pH, thiab lub sijhawm tshuaj tiv thaiv.
Purification thiab filtration:Tom qab cov tshuaj tiv thaiv, cov tshuaj MTHF-Ca tau ua tiav cov txheej txheem purification xws li pom, centrifugation, lossis lwm yam kev sib cais kom tshem tawm cov impurities thiab cov khoom los ntawm cov khoom uas yuav tau tsim thaum lub sij hawm cov tshuaj tiv thaiv.
Qhuav thiab solidification:Cov tshuaj purified MTHF-Ca yog tom qab ntawd ua tiav ntxiv kom tshem tawm cov dej noo ntau dhau thiab ua kom cov khoom kawg. Qhov no tuaj yeem ua tiav los ntawm cov txheej txheem xws li tshuaj tsuag kom qhuav lossis khov-qhuav, nyob ntawm seb cov khoom xav tau.
Kev tswj kom zoo thiab kev sim:Qhov kawg ntawm MTHF-Ca cov khoom yog ua raws li kev tswj xyuas nruj kom ntseeg tau tias nws purity, ruaj khov, thiab ua raws li cov qauv zoo. Qhov no tuaj yeem suav nrog kev sim rau impurities, potency, thiab lwm yam tsis raug.
Ntim thiab khaws cia:MTHF-Ca tau ntim rau hauv cov thawv tsim nyog, ua kom cov ntawv sau kom raug thiab khaws cia kom ruaj khov thiab ruaj khov. Nws feem ntau yog khaws cia rau hauv qhov chaw qhuav, txias kom deb ntawm tshav ntuj ncaj qha.
Cia: Khaws nyob rau hauv qhov chaw txias, qhuav, thiab huv si, tiv thaiv los ntawm noo noo thiab ncaj qha teeb.
Ntim Pob: 25kg / nruas.
Lub Sijhawm Lead: 7 hnub tom qab koj xaj.
Lub neej txee: 2 xyoos.
Lus Cim: Customized specifications kuj tuaj yeem ua tiav.
20kg / hnab 500kg / pallet
Txhim kho ntim
Kev ruaj ntseg logistics
Qhia
Hauv 100kg, 3-5 Hnub
Qhov rooj rau qhov rooj kev pabcuam yooj yim tuaj tos cov khoom
Los ntawm Hiav Txwv
Tshaj 300kg, Nyob ib ncig ntawm 30 Hnub
Chaw nres nkoj rau chaw nres nkoj kev pab cuam clearance broker xav tau
Los ntawm Cua
100kg-1000kg, 5-7days
Tshav dav hlau mus rau tshav dav hlau kev pab cuam clearance broker xav tau
Pure Methyltetrahydrofolate Calcium (5-MTHF-Ca)tau ntawv pov thawj nrog ISO daim ntawv pov thawj, HALAL daim ntawv pov thawj, thiab KOSHER daim ntawv pov thawj.
Qhov sib txawv ntawm plaub tiam ntawm folic acid (5-MTHF) thiab cov tshuaj folic acid nyob rau hauv lawv cov qauv tshuaj thiab bioavailability hauv lub cev.
Chemical structure:Cov tshuaj folic acid yog ib hom hluavtaws ntawm folate uas yuav tsum tau ua ntau yam kev hloov pauv hauv lub cev ua ntej nws tuaj yeem siv tau. Ntawm qhov tod tes, Plaub-tiam folic acid, tseem hu ua 5-MTHF los yog Methyltetrahydrofolate, yog cov nquag, bioavailable folate uas tsis tas yuav hloov dua siab tshiab.
Bioavailability:Cov tshuaj folic acid yuav tsum tau hloov mus rau nws daim ntawv nquag, 5-MTHF, los ntawm cov tshuaj tiv thaiv enzymatic hauv lub cev. Cov txheej txheem hloov dua siab tshiab no txawv ntawm cov tib neeg thiab tuaj yeem cuam tshuam los ntawm kev hloov pauv caj ces lossis lwm yam. Hauv qhov sib piv, 5-MTHF twb nyob hauv nws daim ntawv nquag, ua rau nws yooj yim rau kev siv ntawm tes thiab siv.
Absorption thiab siv:Kev nqus ntawm cov tshuaj folic acid tshwm sim hauv cov hnyuv me, qhov uas nws yuav tsum tau hloov mus rau hauv daim ntawv nquag los ntawm enzyme dihydrofolate reductase (DHFR). Txawm li cas los xij, txoj kev hloov dua siab tshiab no tsis zoo rau qee tus neeg, ua rau txo qis bioavailability. 5-MTHF, yog daim ntawv nquag, yog nkag tau yooj yim thiab siv los ntawm lub cev, hla txoj kev hloov dua siab tshiab. Qhov no ua rau nws nyiam tshaj plaws rau cov tib neeg uas muaj kev hloov pauv caj ces lossis cov xwm txheej uas cuam tshuam rau cov metabolism hauv folate.
Fitness rau qee tus neeg:Vim qhov sib txawv ntawm kev nqus thiab kev siv, 5-MTHF suav tias yog qhov tsim nyog rau cov tib neeg uas muaj qee yam kev hloov pauv caj ces, xws li MTHFR noob hloov, uas tuaj yeem cuam tshuam kev hloov pauv ntawm folic acid rau nws daim ntawv nquag. Rau cov tib neeg no, siv 5-MTHF ncaj qha tuaj yeem ua kom muaj qib folate hauv lub cev thiab txhawb nqa ntau yam kev ua haujlwm lom neeg.
Ntxiv:Cov tshuaj folic acid feem ntau pom muaj nyob rau hauv cov tshuaj ntxiv, cov khoom noj muaj zog, thiab cov khoom noj ua tiav, vim nws ruaj khov thiab tsis tshua muaj nqi los tsim. Txawm li cas los xij, muaj ntau ntxiv ntawm 5-MTHF cov tshuaj ntxiv uas muab daim ntawv nquag ncaj qha, uas tuaj yeem muaj txiaj ntsig zoo rau cov tib neeg uas muaj teeb meem hloov folic acid.
Cov kev mob tshwm sim ntawm Plaub-tiam folic acid (5-MTHF) feem ntau tsis tshua muaj thiab mob me, tab sis nws yog ib qho tseem ceeb kom paub txog cov tshuaj tiv thaiv:
Kev tsis haum tshuaj:Zoo li txhua yam tshuaj ntxiv lossis tshuaj, kev ua xua tuaj yeem ua tau. Cov tsos mob yuav muaj xws li pob khaus, khaus, o, kiv taub hau, lossis ua tsis taus pa. Yog tias koj ntsib ib qho ntawm cov tsos mob no, nrhiav kev kho mob tam sim ntawd.
Cov teeb meem digestive:Qee tus neeg yuav muaj kev tsis xis nyob hauv plab, xws li xeev siab, tsam plab, roj, lossis raws plab. Cov tsos mob no feem ntau yog ib ntus thiab txo qis thaum lub cev hloov kho ntxiv.
Kev sib cuam tshuam nrog cov tshuaj:5-MTHF tuaj yeem cuam tshuam nrog qee yam tshuaj, suav nrog cov tshuaj siv rau kev kho mob qog noj ntshav, tshuaj tiv thaiv kab mob, methotrexate, thiab qee yam tshuaj tua kab mob. Nws yog ib qho tseem ceeb uas yuav tau tham nrog koj tus kws kho mob yog tias koj noj cov tshuaj kom ntseeg tau tias tsis muaj kev cuam tshuam.
Kev noj tshuaj ntau dhau lossis ntau dhau folate:Txawm hais tias tsis tshua muaj, kev noj ntau dhau ntawm folate (xws li 5-MTHF) tuaj yeem ua rau cov ntshav siab folate. Qhov no tuaj yeem npog cov tsos mob ntawm vitamin B12 tsis txaus thiab cuam tshuam rau kev kuaj mob thiab kev kho mob ntawm qee yam mob. Nws yog ib qho tseem ceeb uas yuav tau ua raws li cov lus pom zoo thiab sab laj nrog kws kho mob rau kev taw qhia.
Lwm yam kev xav txog:Cov poj niam cev xeeb tub lossis cov uas npaj yuav cev xeeb tub yuav tsum tham nrog lawv tus kws kho mob ua ntej noj 5-MTHF ntau dua, vim tias kev noj cov folate ntau dhau tuaj yeem npog cov tsos mob ntawm vitamin B12 tsis txaus, uas yog ib qho tseem ceeb rau kev loj hlob ntawm neural tube hauv lub fetus.
Ib yam li kev noj zaub mov lossis tshuaj noj, nws yuav tsum tau sib tham txog kev siv Fourth-generation folic acid (5-MTHF) nrog tus kws kho mob, tshwj xeeb tshaj yog tias koj muaj mob hauv qab los yog noj lwm yam tshuaj. Lawv tuaj yeem muab cov lus qhia tus kheej raws li koj qhov kev xav tau tshwj xeeb thiab pab saib xyuas cov kev mob tshwm sim.
Plaub tiam folic acid, tseem hu ua 5-methyltetrahydrofolate (5-MTHF), yog ib hom tshuaj lom neeg ntawm folate uas tau yooj yim nqus thiab siv los ntawm lub cev piv rau cov tshuaj folic acid ntxiv. Nov yog qee qhov kev tshawb fawb tshawb fawb uas txhawb nqa nws cov txiaj ntsig:
Ntxiv bioavailability:5-MTHF tau pom tias muaj bioavailability ntau dua li folic acid. Ib txoj kev tshawb fawb luam tawm nyob rau hauv American Journal of Clinical Nutrition piv rau bioavailability ntawm folic acid thiab 5-MTHF hauv cov poj niam noj qab haus huv. Nws pom tias 5-MTHF tau nqus sai dua thiab ua rau muaj cov folate ntau dua hauv cov qe ntshav liab.
Txhim kho folate xwm txheej:Ntau qhov kev tshawb fawb tau pom tias kev ntxiv nrog 5-MTHF tuaj yeem ua kom cov ntshav folate tau zoo. Nyob rau hauv ib tug randomized tswj sim luam tawm nyob rau hauv Phau ntawv Journal of Nutrition, cov kws tshawb fawb tau piv cov teebmeem ntawm 5-MTHF thiab folic acid supplementation ntawm folate raws li txoj cai nyob rau hauv cov poj niam noj qab haus huv. Lawv pom tias 5-MTHF muaj txiaj ntsig zoo hauv kev ua kom cov ntshav liab folate ntau dua li cov folic acid.
Txhim kho folic acid metabolism:5-MTHF tau pom tias hla dhau cov kauj ruam enzymatic xav tau rau kev ua kom folic acid thiab koom ncaj qha rau hauv cellular folic acid metabolism. Ib txoj kev tshawb fawb luam tawm nyob rau hauv Phau ntawv Journal of Nutrition thiab Metabolism qhia tau hais tias 5-MTHF supplementation txhim kho intracellular folate metabolism hauv cov tib neeg uas muaj kev hloov pauv hauv cov enzymes koom nrog hauv kev ua kom folic acid.
Txo cov qib homocysteine :Kev nce qib ntawm homocysteine , ib qho amino acid hauv cov ntshav, cuam tshuam nrog kev pheej hmoo ntawm cov kab mob plawv. Cov kev tshawb fawb tau pom tias 5-MTHF supplementation tuaj yeem txo cov qib homocysteine . Ib qho kev tshuaj ntsuam meta-tshaj tawm nyob rau hauv Phau Ntawv Xov Xwm ntawm American College of Nutrition tsom xam 29 randomized tswj kev sim thiab xaus lus tias 5-MTHF supplementation muaj txiaj ntsig zoo dua li folic acid hauv kev txo cov qib homocysteine .
Nws yog ib qho tseem ceeb uas yuav tsum nco ntsoov tias ib tus neeg cov lus teb rau kev ntxiv yuav txawv, thiab qhov ua tau zoo ntawm 5-MTHF tuaj yeem nyob ntawm cov yam ntxwv xws li kev hloov pauv caj ces hauv folate metabolism enzymes thiab tag nrho kev noj haus. Nws yog ib txwm pom zoo kom sab laj nrog ib tus kws kho mob rau cov lus qhia ntawm tus kheej hais txog kev noj tshuaj ntxiv thiab sib tham txog kev txhawj xeeb txog kev noj qab haus huv lossis cov xwm txheej tshwj xeeb.
